Results 41 to 50 of about 72,124 (260)

Braided affine geometry and q-analogs of wave operators

, 2009
The main goal of this review is to compare different approaches to constructing geometry associated with a Hecke type braiding (in particular, with that related to the quantum group U_q(sl(n))).
Gurevich, Dimitri, Saponov, Pavel
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Indefinite Affine Hyperspheres Admitting a Pointwise Symmetry. Part 2

Symmetry, Integrability and Geometry: Methods and Applications, 2009
An affine hypersurface M is said to admit a pointwise symmetry, if there exists a subgroup G of Aut(T_pM) for all p in M, which preserves (pointwise) the affine metric h, the difference tensor K and the affine shape operator S.
Christine Scharlach
doaj   +1 more source

A New Supersymmetric Index

, 1992
We show that ${\rm Tr}(-1)^F F e^{-\beta H}$ is an index for $N$=2 supersymmetric theories in two dimensions, in the sense that it is independent of almost all deformations of the theory.
Abdalla, Abdalla, Alvarez-Gaumé, Bernard, Bott, Bourdeau, Callias, Cardy, Cecotti, Cecotti, Cecotti, Cecotti, Cecotti, Cumrun Vafa, Dijkgraaf, Dixon, Eguchi, Fendley, Fendley, Fendley, Fendley, Fendley, Ferrara, Gates, Gepner, Goldstone, Imbimbo, Intriligator, Jackiw, Kastor, Kaul, Ken Intriligator, Klassen, Kobayashi, Landau, Lerche, Martinec, Mathieu, McCoy, Narain, Nemeschansky, Niemi, Paul Fendley, Ray, Ray, Reed, Sergio Cecotti, Vafa, Vafa, Waterson, Witten, Witten, Witten, Witten, Zamolodchikov, Zamolodchikov, Zamolodchikov, Zamolodchikov, Zamolodchikov   +58 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Nonlinear Observability Algorithms with Known and Unknown Inputs: Analysis and Implementation

Mathematics, 2020
The observability of a dynamical system is affected by the presence of external inputs, either known (such as control actions) or unknown (disturbances).
Nerea Martínez, Alejandro F. Villaverde
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Riemannian Metrics on Locally Projectively Flat Manifolds

, 2001
The expression (-1/u) times the Hessian of u transforms as a symmetric (0,2) tensor under projective coordinate transformations, so long as u transforms as a section of a certain line bundle.
Loftin, J. C.
core   +2 more sources

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

On the dimension of Lie algebras of infinitesimal affine transformations of direct products of more than two spaces of affine connection of the first type

Дифференциальная геометрия многообразий фигур
The theory of motions in generalized spaces is one of the directions in modern differential geometry. Such scientists as E. Cartan, P. K. Rashev­sky, P. A. Shirokov, I. P. Egorov, A.Ya. Sultanov and other scientists were engaged in the study of movements
Glebova M. V. , Sultanov A.Ya.
doaj   +1 more source