Results 81 to 90 of about 401,072 (287)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Transient behavior of affine projection algorithms

open access: yes
Most analytical results on affine projection algorithms assume special regression models or Gaussian regression data. The available analyses also treat different affine projection filters separately.
Shin, Hyun-Chool, Sayed, Ali H.
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Curious Characterizations of Projective and Affine Geometries

open access: yesAdvances in Applied Mathematics, 2002
In the spirit of \textit{J. E. Bonin} and \textit{W. P. Miller} [Eur. J. Comb. 20, No. 8, 713-724 (1999; Zbl 0946.05020)], the author provides several characterization theorems for finite projective and affine geometries, such as ``If any three of the following four matroid invariants of a rank-\(n\) combinatorial geometry -- the number of points, the ...
openaire   +1 more source

An Affine Projection Algorithm with Evolving Order

open access: yes, 2019
We present a novel affine projection algorithm (APA) which automatically determines its projection order by an evolutionary method. The evolutionary method increases or decreases the projection order by comparing the output error with a threshold.
Kim, SE, SONG, WOO JIN, Kong, Se-Jin
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Equivalence of Some Affine Isoperimetric Inequalities

open access: yesJournal of Inequalities and Applications, 2009
We establish the equivalence of some affine isoperimetric inequalities which include the -Petty projection inequality, the -Busemann-Petty centroid inequality, the "dual" -Petty projection inequality, and the "dual" -Busemann-Petty inequality.
Yu Wuyang
doaj  

Object-Image Correspondence for Algebraic Curves under Projections

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2013
We present a novel algorithm for deciding whether a given planar curve is an image of a given spatial curve, obtained by a central or a parallel projection with unknown parameters.
Joseph M. Burdis   +2 more
doaj   +1 more source

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