Results 91 to 100 of about 12,502 (286)

Affine Anosov representations

In this survey article we discuss about possible generalizations of Anosov representations in the affine setting and their consequences.
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Affine representations of generalized quadrangles

Journal of Algebra, 1970
AbstractIt is shown that a general construction due to Tits of finite generalized quadrangles (4-gons) yields the “classical” examples and only these except when the characteristic of the underlying field is 2. In that case an affine representation of the quadrangles is used to obtain results concerning the self-duality and self-polarity of a “nice ...
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Affine Non-negative Collaborative Representation Based Pattern Classification [PDF]

, 2020
He-Feng Yin, Xiao‐Jun Wu, Zhenhua Feng, Josef Kittler   +3 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Optimization Procedures in Affine Model Checking

Моделирование и анализ информационных систем, 2011
Symbolic model checking is based on a compact representation of sets of states and transition relations. At present there are three basic approaches of symbolic model checking: BDD-methods, bounded model checking using SAT-solvers, and various algebraic ...
N. O. Garanina
doaj  

Quasi-polynomial representations of double affine Hecke algebras

Forum of Mathematics, Sigma
We introduce an explicit family of representations of the double affine Hecke algebra $\mathbb {H}$ acting on spaces of quasi-polynomials, defined in terms of truncated Demazure-Lusztig type operators.
Siddhartha Sahi, Jasper Stokman, Vidya Venkateswaran   +2 more
doaj   +1 more source

On the universal representation of the scattering matrix of affine Toda field theory [PDF]

, 2000
Andreas Fring, Christian Korff, Bruno Schulz   +2 more
openalex   +1 more source