Instanton R-matrix and W $$ \mathcal{W} $$ -symmetry
Journal of High Energy Physics, 2019 We study the relation between W 1 + ∞ $$ {\mathcal{W}}_{1+\infty } $$ algebra and Arbesfeld-Schiffmann Tsymbaliuk Yangian using the Maulik-Okounkov R-matrix. The central object linking these two pictures is the Miura transformation. Using the results of
Tomáš Procházka
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Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Optimal quadratic full state feedback control of nonlinear affine systems
Franklin OpenThe solution of the optimal quadratic full-state feedback closed-loop control of a nonlinear affine system problem is presented and solved. This solution uses the State-Dependent Coefficient (SDC) form of a nonlinear system and the Calculus of Variations.
Ilan Rusnak
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FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
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A new 3D representation and compression algorithm for non-rigid moving objects using affine-octree [PDF]
, 2009 Youyou Wang, Guilherme N. De Souza
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A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
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Affine.m—Mathematica package for computations in representation theory of finite-dimensional and affine Lie algebras [PDF]
, 2012 Anton Nazarov
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Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
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Affine group representation formalism for four-dimensional, Lorentzian, quantum gravity [PDF]
, 2013 Ching-Yi Chou, Eyo Eyo Ita, Chopin Soo
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Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source