Results 41 to 50 of about 152,745 (261)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Local martingales associated with Schramm-Loewner evolutions with internal symmetry

open access: yes, 2018
We consider Schramm-Loewner evolutions (SLEs) with internal degrees of freedom that are associated with representations of affine Lie algebras, following group theoretical formulation of SLEs. We reconstruct the SLEs considered by Bettelheim {\it et al.}
Koshida, Shinji
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

On affine motions with one-dimensional orbits in common spaces of paths

open access: yesДифференциальная геометрия многообразий фигур
The concept of a common path space was introduced by J. Duqlas. M. S. Knebelman was the first to consider affine and projective move­ments in these spaces. The general path space is a generalization of the space of affine connectivity.
N. D. Nikitin, O. G. Nikitina
doaj   +1 more source

3D fermions and affine Yangian

open access: yesNuclear Physics B, 2021
2D (dimensional) Boson-Fermion correspondence is a well-known object. In this paper, we define 3D Fermions Γm→ and Γm→⁎ for any vertex m→ and the representation space F, we find that F is isomorphic to the vector space of 3D Young diagrams. Operators Γm→
Na Wang
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Robust Image Recovery via Affine Transformation and $L_{2,1}$ Norm

open access: yesIEEE Access, 2019
In this paper, we propose a novel robust algorithm for image recovery via affine transformations and the L2,1 norm. To be robust against miscellaneous adverse effects such as occlusions, outliers, and heavy sparse noise, the new algorithm integrates ...
Habte Tadesse Likassa   +2 more
doaj   +1 more source

A representation-theoretic proof of the branching rule for Macdonald polynomials [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2015
We give a new representation-theoretic proof of the branching rule for Macdonald polynomials using the Etingof-Kirillov Jr. expression for Macdonald polynomials as traces of intertwiners of $U_q(gl_n)$. In the Gelfand-Tsetlin basis, we show that diagonal
Yi Sun
doaj   +1 more source

Inonu-Wigner Contractions of Kac-Moody Algebras

open access: yes, 1992
We discuss In\"on\"u-Wigner contractions of affine Kac-Moody algebras. We show that the Sugawara construction for the contracted affine algebra exists only for a fixed value of the level $k$, which is determined in terms of the dimension of the ...
Majumdar, Parthasarathi
core   +1 more source

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