Results 51 to 60 of about 12,502 (286)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On affine motions with one-dimensional orbits in common spaces of paths

open access: yesДифференциальная геометрия многообразий фигур
The concept of a common path space was introduced by J. Duqlas. M. S. Knebelman was the first to consider affine and projective move­ments in these spaces. The general path space is a generalization of the space of affine connectivity.
N. D. Nikitin, O. G. Nikitina
doaj   +1 more source

Finite-Dimensional Representations of Quantum Affine Algebras

open access: yesPublications of the Research Institute for Mathematical Sciences, 1997
We present a conjecture on the irreducibility of the tensor products of fundamental representations of quantized affme algebras. This conjecture implies in particular that the irreducibility of the tensor products of fundamental representations is completely described by the poles of R
Akasaka, Tatsuya, Kashiwara, Masaki
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Small Representations for Affine q-Schur Algebras [PDF]

open access: yesAlgebras and Representation Theory, 2015
When the parameter $q\in\mathbb C^*$ is not a root of unity, simple modules of affine $q$-Schur algebras have been classified in terms of Frenkel--Mukhin's dominant Drinfeld polynomials (\cite[4.6.8]{DDF}). We compute these Drinfeld polynomials associated with the simple modules of an affine $q$-Schur algebra which come from the simple modules of the ...
Du, Jie, Fu, Qiang
openaire   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Robust Image Recovery via Affine Transformation and $L_{2,1}$ Norm

open access: yesIEEE Access, 2019
In this paper, we propose a novel robust algorithm for image recovery via affine transformations and the L2,1 norm. To be robust against miscellaneous adverse effects such as occlusions, outliers, and heavy sparse noise, the new algorithm integrates ...
Habte Tadesse Likassa   +2 more
doaj   +1 more source

A representation-theoretic proof of the branching rule for Macdonald polynomials [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2015
We give a new representation-theoretic proof of the branching rule for Macdonald polynomials using the Etingof-Kirillov Jr. expression for Macdonald polynomials as traces of intertwiners of $U_q(gl_n)$. In the Gelfand-Tsetlin basis, we show that diagonal
Yi Sun
doaj   +1 more source

Home - About - Disclaimer - Privacy