Results 91 to 100 of about 243,977 (284)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
On hypersurfaces in a locally affine Riemannian Banach manifold II
International Journal of Mathematics and Mathematical Sciences, 2004 In our previous work (2002), we proved that an essential second-order hypersurface in an infinite-dimensional locally affine Riemannian Banach manifold is a Riemannian manifold of constant nonzero curvature.
El-Said R. Lashin, Tarek F. Mersal
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Geometry of distribution of flags in an even-dimensional affine space
Lietuvos Matematikos Rinkinys, 2002 In this article the problem of intrinsic normalizations of distribution of flags in an even-dimensional affine space is considered.
Kazimieras Navickis
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AFFINE GEOMETRY OF SPINE SPACES
Demonstratio Mathematica, 2003 A spine space is a partial linear space, where the set of points is formed as a collection of certain \(k\)-subspaces of a vector space, while the lines are certain pencils of \(k\)-subspaces lying in between a \((k-1)\)- and a \((k+1)\)-subspace. It is possible to define affine lines and on those a natural parallel-relation.
Prażmowski, Krzysztof, Żynel, Mariusz
openaire +2 more sources
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Nédélec spaces in affine coordinates
Computers & Mathematics with Applications, 2005 In this note, we provide a conveniently implementable basis for simplicial Nédélec spaces of any order in any space dimension. The main feature of the basis is that it is expressed solely in terms of the barycentric coordinates of the simplex.
Department of Mathematics, University of Florida Gainesville, FL 32611-8105, U.S.A. ( host institution ) +3 more
openaire +4 more sources
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
A simple fuzzy control design for powertrain systems with three inertias [PDF]
Memoirs of the Scientific Sections of the Romanian Academy, 2013 This paper proposes a simple fuzzy control design for powertrain systems with three inertias. Considering four operating modes of the clutch, the piecewise affine state-space models offers an accurate characterization of the powertrain systems as ...
Radu-Emil Precup +4 more
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