Results 51 to 60 of about 243,977 (284)

Affinity spaces

ASCILITE Publications
This poster (Padlet ‘Collaborative reflection on AI’) showcases a professional development approach that uses Padlet as an affinity space (Gee, 2004; Honeychurch, 2023) for educators to collaboratively explore and reflect on their experiences with Generative AI (GenAI) in education.
Alison Casey, Wendy Taleo, Carmen Vallis, Penny Wheeler   +3 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Lightlike simultaneity, comoving observers and distances in general relativity

, 2006
We state a condition for an observer to be comoving with another observer in general relativity, based on the concept of lightlike simultaneity. Taking into account this condition, we study relative velocities, Doppler effect and light aberration.
Beem, Bolós, Crawford, Helgason, Misner, Newman, Olivert, Rindler, Sachs, Synge, Vicente J. Bolós   +10 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Fractional Curvatures of Equiaffine Curves in Three-Dimensional Affine Space

Journal of New Theory
This paper presents a method for computing the curvatures of equiaffine curves in three-dimensional affine space by utilizing local fractional derivatives.
Meltem Öğrenmiş
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Oriented angles in affine space

Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2004
The concept of a smooth oriented angle in an arbitrary affine space is introduced. This concept is based on a kinematics concept of a run. Also, a concept of an oriented angle in such a space is considered.
Włodzimierz Waliszewski
doaj  

Diagrams for nonabelian Hodge spaces on the affine line

Comptes Rendus. Mathématique, 2020
In this announcement a diagram will be defined for each nonabelian Hodge space on the affine line.
Boalch, Philip, Yamakawa, Daisuke
doaj   +1 more source

Affine Toda field theory as a 3-dimensional integrable system

, 1995
The affine Toda field theory is studied as a 2+1-dimensional system. The third dimension appears as the discrete space dimension, corresponding to the simple roots in the $A_N$ affine root system, enumerated according to the cyclic order on the $A_N ...
Kashaev, R. M., Reshetikhin, N.
core   +1 more source