Results 61 to 70 of about 243,977 (284)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Online identification of stability region for large-scale wind farms, Part I: Clustering based piecewise affine impedance modeling

International Journal of Electrical Power & Energy Systems
The online assessment of the small-signal stability of wind farms faces challenges in accurately identifying impedance due to the unknown structure and parameters of wind turbine generators.
Jia Luo, Peng Wang, Haoran Zhao, Chenxinwei Yuan, Tiancheng Liu, Vladimir Terzija   +5 more
doaj   +1 more source

Carrollian and celestial spaces at infinity

Journal of High Energy Physics, 2022
We show that the geometry of the asymptotic infinities of Minkowski spacetime (in d + 1 dimensions) is captured by homogeneous spaces of the Poincaré group: the blow-ups of spatial (Spi) and timelike (Ti) infinities in the sense of Ashtekar-Hansen and a ...
José Figueroa-O’Farrill, Emil Have, Stefan Prohazka, Jakob Salzer   +3 more
doaj   +1 more source

Spin Chain Hamiltonians with Affine $U_q g$ symmetry

, 1995
We construct the family of spin chain Hamiltonians, which have affine $U_q g$ guantum group symmetry. Their eigenvalues coincides with the eigenvalues of the usual spin chain Hamiltonians which have non-affine $U_q g_0$ quantum group symmetry, but have ...
A. Sedrakyan, Davies, Drinfeld, Haldane, Inozemtsev, Jimbo, Jimbo, Martin, Moore, Pasquier, Prester, Rittenberg, Shastry, Sierra, T. Hakobyan   +14 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Affine Geometrical Region CNN for Object Tracking

IEEE Access, 2020
The state-of-the-art trackers using deep learning technology have little special strategy to gain the bounding box well when the target suffers drastic geometric deformation.
Yinghong Xie, Jie Shen, Chengdong Wu
doaj   +1 more source

The Solutions of Affine and Conformal Affine Toda Field Theories

, 1994
We give new formulations of the solutions of the field equations of the affine Toda and conformal affine Toda theories on a cylinder and two-dimensional Minkowski space-time.
Papadopoulos, G., Spence, B.
core   +1 more source

Affine attenuated spaces

Journal of Combinatorial Theory, Series A, 1993
The rank \(d\) geometries satisfying the Intersection Property and with the following diagram are classified when \(s>3\) and \(d \geq 4\): \[ {\underset{s-1}\circ} {\overset{Af}{\text{---}}} {\underset{s}\circ} {\text{---}} {\underset{s}\circ} \cdots {\underset{s}\circ} {\overset{N^*}{\text{---}}} {\underset{t}\circ} . \]
DEL FRA A., GHINELLI D., PASINI, ANTONIO
openaire   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Convergence of generic infinite products of affine operators

Abstract and Applied Analysis, 1999
We establish several results concerning the asymptotic behavior of random infinite products of generic sequences of affine uniformly continuous operators on bounded closed convex subsets of a Banach space.
S. Reich, A. J. Zaslavski
doaj   +1 more source