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HELIN Cataloging Affinity Group minutes for 08/14/13
Minutes of the Cataloging Affinity Group of the HELIN Consortium for August ...
HELIN Consortium. Cataloging Affinity Group
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Extended affinization of Invariant Affine Reflection Algebras
Invariant affine reflection algebras are the last and the most general known extension of affine Kac-Moody Lie algebras, introduced in recent years. We develop a method known as "affinization" to the class of invariant affine reflection algebras, and show that starting with an algebra from this class together with a certain finite order automorphism ...
Azam, Saeid +2 more
openaire +4 more sources
HELIN Serials Affinity Group minutes for 4/26/11
Minutes of the Serials Affinity Group of the HELIN Consortium for April ...
HELIN Consortium. Serials Affinity Group
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Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
HELIN Serials Affinity Group minutes for 03/12/13
Minutes of the Serials Affinity Group of the HELIN Consortium for March ...
HELIN Consortium. Serials Affinity Group
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
HELIN Serials Affinity Group minutes for 10/1/10
Minutes of the Serials Affinity Group of the HELIN Consortium for October ...
HELIN Consortium. Serials Affinity Group
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
HELIN Cataloging Affinity Group minutes for 1/13/14
Minutes of the Cataloging Affinity Group of the HELIN Consortium for January ...
HELIN Consortium. Cataloging Affinity Group
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