Results 71 to 80 of about 24,078 (230)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

China’s New Housing Security Model: Evaluation of the Job–Housing Balance in Affordable Rental Housing, Shanghai

open access: yesLand
The Chinese government’s recent low-income housing scheme aims to tackle housing challenges faced by the urban floating population. A notable shift in this initiative is the focus on the job–housing balance.
Peihong Wang, Kerun Li, Wenbing Zhang
doaj   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

open access: yesAdvanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu   +9 more
wiley   +1 more source

Strategic Interaction in the Supply of Affordable Housing Construction Land: Evidence from China’s Cities

open access: yesBuildings
This study examines strategic interaction effects in the supply of affordable housing construction land among Chinese urban governments. Existing studies have predominantly examined China’s subsidized housing land supply from a vertical intergovernmental
Zhen Wang   +3 more
doaj   +1 more source

Multiparametric Bioresorbable Sensor for Doxorubicin Detection via Molecularly Imprinted Synthetic Receptors

open access: yesAdvanced Science, EarlyView.
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi   +11 more
wiley   +1 more source

The Impact of Housing Space Standards on Adaptability in Affordable Multifamily Housing: An Analytical Study of User Modifications in Sulaymaniyah, Iraq

open access: yesArchitecture
Affordable housing has evolved to meet the difficulties of increased demand by offering acceptable living spaces for middle- to low-income families and facilitating access to housing units based on their annual income.
Nahedh Al-Qemaqchi, Maha Al-Qemaqchi
doaj   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

open access: yesAdvanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

RVs as Affordable Housing

open access: yesVisions in Leisure and Business, 2023
George Allen
doaj   +1 more source

Compositional Tuning and Surface Restructuring Synergistically Enhance Perovskite Ferrite Catalysts for Hydrogen Evolution in a Membrane‐Less Electrolyzer

open access: yesAdvanced Energy Materials, EarlyView.
In this work, a self‐restructuring Fe‐based perovskite catalyst is developed, leveraging in situ amorphization to achieve a “self‐improving” behavior for hydrogen evolution. When integrated into a custom‐built membrane‐less electrolyzer, the system demonstrates a record‐breaking 1000 h stability, providing a robust and practical pathway for the ...
Yixin Bi   +8 more
wiley   +1 more source

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