Results 41 to 50 of about 40,400 (295)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The impact of mHealth apps’ affordance on consumers’ novel food purchasing decisions

open access: yesData Science and Management
Mobile health apps (MHAs) provide users with exercise support and dietary recommendations. They also suggest a wide range of novel foods. However, some users may face food neophobia, a reluctance to try unfamiliar foods, as well as the “omnivore’s ...
Yunfan Lu   +3 more
doaj   +1 more source

Affordance Perceptions under Malleable Information Technology: A Social Cognitive Theory Perspective [PDF]

open access: yes, 2019
Organizations benefit from malleable IT only if users perceive the affordances that malleable IT provides for their work. However, theoretical explanations and empirical evidence related to affordance perception are scarce.
Dibbern, Jens   +2 more
core  

Telepresence and the Role of the Senses [PDF]

open access: yes, 2019
The telepresence experience can be evoked in a number of ways. A well-known example is a player of videogames who reports about a telepresence experience, a subjective experience of being in one place or environment, even when physically situated in ...
AA Ozok   +59 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Exploring the Gamification Affordances in Online Shopping with the Heterogeneity Examination through REBUS-PLS

open access: yesJournal of Theoretical and Applied Electronic Commerce Research, 2023
This study investigates, from the perspective of affordance theory, how the implementation of gamification features and mechanisms in online-shopping platforms enable consumers to enjoy immersive shopping experiences and make subsequent shopping ...
Xiao-Yu Xu   +3 more
doaj   +1 more source

Can Rats Reason? [PDF]

open access: yes, 2015
Since at least the mid-1980s claims have been made for rationality in rats. For example, that rats are capable of inferential reasoning (Blaisdell, Sawa, Leising, & Waldmann, 2006; Bunsey & Eichenbaum, 1996), or that they can make ...
Stephane, Savanah
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Not all the bots are created equal:the Ordering Turing Test for the labelling of bots in MMORPGs [PDF]

open access: yes, 2017
This article contributes to the research on bots in Social Media. It takes as its starting point an emerging perspective which proposes that we should abandon the investigation of the Turing Test and the functional aspects of bots in favor of studying ...
Becker H.   +7 more
core   +2 more sources

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy