Results 41 to 50 of about 7,241,958 (280)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Once Again, the Doorknob: Affordance, Forgiveness, and Ambiguity in Human-Computer Interaction and Human-Robot Interaction

Media Theory, 2019
Based on the author’s keynote lecture at the 2018 ‘Rethinking Affordance’ symposium (Stuttgart, Germany), this essay offers a comprehensive survey of the tensions between J.J. Gibson’s and Don Norman’s perspectives on the concept of affordance,
Olia Lialina
doaj   +1 more source

How the Materials of Objects Shape Consumption: An Affordance Theory Perspective

Journal of Consumer Research
Glasses and stones, metals and textiles, leathers and plastics…The materials of objects can shape consumption in a variety of ways. Drawing on affordance theory, the authors conceptualize materials as prominent drivers of object affordances, that is ...
Roman Pavlyuchenko, Delphine Dion
semanticscholar   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Landscape Visual Affordance Evaluation at a Regional Scale in National Parks: A Case Study of the Changhong Area in Qianjiangyuan National Park

Land
National parks play a vital role in safeguarding natural scenery, maintaining ecological integrity, and preserving cultural heritage, while simultaneously offering valuable opportunities for recreation and education.
Yuchen Dong, Yuan Kang, Chengzhao Wu
doaj   +1 more source

A Comprehensive Review of Affordance Theory in Enhancing Digital Health Solutions

Technium
The interplay between humans and objects is a foundational aspect of visual perception, significantly enriched by Gibson's introduction of Affordance Theory.
Zhengyang Liu, Albert Young Choi
semanticscholar   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Biofunctional Understanding and Judgment of Size

Frontiers in Psychology, 2016
Research has shown that the meaningfulness of the material increases judged size, whereas symmetry decreases size judgments. These findings have been interpreted in terms of information processing, with a greater quantity of information leading to a ...
Zheng Jin, Zheng Jin, Yang Lee, Yang Lee, Zheng Yuan   +4 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Rethinking Affordance

Media Theory, 2019
This article introduces the special issue 'Rethinking Affordance'. 
Ashley Scarlett, Martin Zeilinger
doaj   +1 more source