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Diagnostic Ambiguity in Apical Hypertrophic Cardiomyopathy: Case-Based Insights and Review of Evolving Criteria. [PDF]

open access: yesJACC Case Rep
Li-Jedras M   +5 more
europepmc   +1 more source

Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy: from Pathophysiology To Real World Data. [PDF]

open access: yesCurr Cardiol Rep
Panichella G   +8 more
europepmc   +1 more source
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Aficamten: A Breakthrough Therapy for Symptomatic Obstructive Hypertrophic Cardiomyopathy

American Journal of Cardiovascular Drugs, 2023
Aficamten is a novel cardiac myosin inhibitor that has demonstrated its ability to safely lower left ventricular outflow tract (LVOT) gradients and improve heart failure symptoms in patients with obstructive hypertrophic cardiomyopathy (HCM). Based on the REDWOOD-HCM open label extension (OLE) study, participants receiving aficamten had significantly ...
Sneha Annie Sebastian   +3 more
openaire   +2 more sources

Aficamten—A Second in Class Cardiac Myosin Inhibitor for Hypertrophic Cardiomyopathy

Cardiology in Review, 2023
Hypertrophic cardiomyopathy is an under-recognized disease with a genetic component that results in abnormal and often asymmetric thickening of the left ventricle in addition to decreased compliance and progressive fibrosis of the myocardium. It further poses significant complications related to dynamic left ventricular outflow obstruction over time in
Jay, Patel   +4 more
openaire   +2 more sources

Aficamten in non‐obstructive hypertrophic cardiomyopathy: Unlocking new horizons?

European Journal of Heart Failure
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Rossi, Maddalena   +2 more
openaire   +3 more sources

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