Results 101 to 110 of about 66,840 (266)
Enterovirus infections in children
Pediatric Investigation, EarlyView.Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen +11 more
wiley +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Head‐to‐Head Comparison of Four Ultrasound Elastography Techniques in Detecting Advanced Fibrosis
Portal Hypertension &Cirrhosis, EarlyView.Elastography is an important noninvasive method for diagnosing advanced fibrosis (AF); however, evidence remains insufficient, particularly regarding acoustic radiation force impulse (ARFI) techniques. This prospective mulitcenter study concludes that vibration controlled transient elastography (VCTE) demonstrates superior diagnostic performance to ...
Jiahao Han +8 more
wiley +1 more source
Diagnostic value of Midkine and AFP in the detection of hepatocellular carcinoma: A systematic review and meta-analysis [PDF]
Caspian Journal of Internal MedicineBackground: Hepatocellular carcinoma (HCC) posed significant health problems and deaths. There are various challenges in the management of HCC, including the late detection or diagnosis.
Masrul Lubis +3 more
doaj
Precision Radiation Oncology, EarlyView.The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu +4 more
wiley +1 more source
Vapor‐Phase Detection of Perfluoroalkyl Acids using Amplifying Fluorescent Polymers
Small Methods, EarlyView.Amplifying fluorescent fluorous polymers respond to PFAS vapors in under 5 s. The fluorophilic nature of the polymers results in strong binding and selectivity. ABSTRACT Perfluoroalkyl acids are a subclass of persistent toxic per‐ and polyfluoroalkyl substances (PFAS) whose volatility enables airborne exposure pathways that remain largely unmonitored ...
Jesús Castro‐Esteban +2 more
wiley +1 more source
Small Methods, EarlyView.Van der Waals interactions are reviewed through the lens of advanced atomic force microscopy, highlighting recent progress in nanoscale quantification of Hamaker constants. Emerging methodologies enable high‐resolution mapping of intermolecular forces in 2D materials and biological systems, bridging experimental measurements with quantum‐informed ...
Amir Farokh Payam +2 more
wiley +1 more source
VIEW, EarlyView.Hepatocellular carcinoma (HCC) is frequently resistant to targeted therapies. We identify protein phosphatase Mg2+/Mn2+‐dependent 1G (PPM1G) as a key phosphatase that stabilizes mesenchymal‐epithelial transition factor (MET) by inhibiting its ubiquitination, thereby sustaining protein kinase B (AKT) signaling and promoting Twist‐mediated epithelial ...
Weixun Wu +8 more
wiley +1 more source