Results 31 to 40 of about 270,747 (315)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Webinar: Mechanisms, funding and state capability for poverty and inequality reduction (post-Covid) in South Africa [PDF]
, 2021 WebinarThe Standing Committee on the Science for the Reduction of Poverty and Inequality (SCSfRPI) is a committee of the Academy of Science of South Africa (ASSAf). In July 2020, the ASSAf Council mandated the committee to focus on poverty and inequality
Academy of Science of South Africa (ASSAf)
core
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Gates Open Research, 2021 Background Cape Town, a South African city with high levels of economic inequality, has gone through two COVID-19 waves. There is evidence globally that low-income communities experience higher levels of morbidity and mortality during the pandemic ...
Hannah Hussey +8 more
doaj +1 more source
Group B Streptococcus Serotypes in Pregnant Women From the Western Cape Region of South Africa [PDF]
, 2018 Background: Maternal colonization of Group B streptococci (GBS) during pregnancy is an important risk factor for neonatal morbidity and mortality. The aim of this study was to determine the prevalence and serotype distribution of GBS isolated from a ...
Charlene W. J. Africa +3 more
core +1 more source
Sex Differences in Medication Discontinuation in Axial Spondyloarthritis
Arthritis Care &Research, EarlyView.Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall +9 more
wiley +1 more source
International Journal of Electrochemical Science, 2011 The electrochemical impedance spectroscopy of generation 2 poly(propylene thiophenoimine)-co-poly(3,4 ethylene dioxythiophene) dendritic star copolymer (G2PPT-co-PEDOT) film was studied in LiClO4 solution.
Rasaq A Olowu +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr +16 more
wiley +1 more source
Higher education institutional student wellness support practices during COVID-19 in developing countries [PDF]
Social Sciences and Education Research ReviewCOVID-19 forced many higher education institutions (HEIs) into a reactive shift in their teaching and learning modes. Along with such changes, the need to develop and implement appropriate institutional student wellness support practices in developing ...
LUCKY SIBANDA +2 more
doaj +1 more source