Results 61 to 70 of about 270,747 (315)

Municipal Law Making under SPLUMA: A Survey of Fifteen "First Generation" Municipal Planning By-Laws

open access: yesPotchefstroom Electronic Law Journal, 2019
The legal framework for spatial planning and land use management changed with the introduction of the new Spatial Planning and Land Use Management Act 16 of 2013 (SPLUMA).
Jaap de Visser, Xavia Siyabonga Poswa
doaj   +1 more source

Critical evaluation of the contractor development programme in the Western Cape department of transport and public works: Skills development, training and youth placement, 2015 – 2018

open access: yes, 2021
Masters in Public Administration - MPAEmerging contractors play a significant role in the employment and skills development landscape as they are the employers of unskilled and semi-skilled labour in the construction industry (Western Cape Department of ...
Africa, Monique
core  

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Dermatophytosis in Western Africa: A Review

open access: yesPakistan Journal of Biological Sciences, 2010
Dermatophytic fungal infections are one of the most common infectious diseases in the world and are among the most commonly diagnosed skin diseases in Africa. They are caused by several dermatophyte species made up of three genera: Trichophyton, Microsporum and Epidermophyton.
openaire   +2 more sources

Chinese and Western Investments in Africa: A Comparative Analysis [PDF]

open access: yesInternational Critical Thought, 2020
Chinese investments in African countries have increased massively in the last two decades. Critics have been vociferous for or against the Afro-Chinese relationship depending on their convictions making it a bit difficult to have an objective analysis on the issue.African nations and their leaders have repeatedly shown preference for Western culture ...
openaire   +2 more sources

Spatial analysis of archaeological sites in the Western Cape using an integrated digital archive

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 117-131).This thesis presents the digital amalgamation of eleven collections spanning six decades of archaeological research in the south-western Cape of South ...
Wiltshire, Nicolas
core  

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun   +11 more
wiley   +1 more source

Severe outcomes among adults with TB during COVID-19

open access: yesIJTLD Open
BACKGROUND: The COVID-19 pandemic prompted strict public health measures to reduce SARS-CoV-2 transmission, potentially interrupting TB programmes in the Western Cape, South Africa.
T. Jacobs   +7 more
doaj   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

A low-cost flow cytometric assay for the detection and quantification of apoptosis using an anionic halogenated fluorescein dye

open access: yesBioTechniques, 2008
We describe here a technical improvement of an established colorimetric method used to detect and measure the occurrence of apoptosis in mammalian cells during in vitro cell culture. This assay uses an anionic halogenated fluorescein dye that is taken up
Mervin Meyer   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy