Results 21 to 30 of about 3,885,799 (305)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Child migrants in Africa [PDF]

, 2011
Child Migration in Africa explores the mobility of children without their parents within West Africa. Drawing on the experiences of children from rural Burkina Faso and Ghana, the book provides rich material on the circumstances of children's voluntary ...
Hashim, Iman, Thorsen, Dorte
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

La distribución a través de la teoría : difusión y adaptación de los nuevos esquemas distributivos

Espacio, Tiempo y Forma. Serie VII, Historia del Arte, 1994
El estudio y análisis de la «distribución» en su «concepto» nos lleva a profundizar sobre los distintos significados y contenidos que se han ido produciendo a través del tiempo y, sobre todo, lo que ello significa para la arquitectura.
África Martínez Medina
doaj   +1 more source

Reconstructing the timing and dispersion routes of HIV-1 subtype B epidemics in the Caribbean and Central America: a phylogenetic story. [PDF]

PLoS ONE, 2013
The Caribbean and Central America are among the regions with highest HIV-1B prevalence worldwide. Despite of this high virus burden, little is known about the timing and the migration patterns of HIV-1B in these regions.
Israel Pagán, Africa Holguín
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Carmen de Burgos "Colombine", critica feminista del arte

Espacio, Tiempo y Forma. Serie VII, Historia del Arte, 2006
En las tres primeras décadas del siglo XX, coincidiendo con la difusión del feminismo en España, sobresalió la figura de Carmen de Burgos «Colombine». Fue una prolífica periodista y escritora, de gran conciencia social; sobre todo feminista. Lo ponen de
África Cabanillas Casafranca
doaj   +1 more source

Finite size effects in ferromagnetic spin chains and quantum corrections to classical strings

, 2005
N=4 supersymmetric Yang-Mills operators carrying large charges are dual to semiclassical strings in AdS_5xS^5. The spectrum of anomalous dimensions of very large operators has been calculated solving the Bethe ansatz equations in the thermodynamic limit,
Hernandez, Rafael, Lopez, Esperanza, Perianez, Africa, Sierra, German   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

REVISITING INTERNATIONAL RELATIONS THEORY: DISCOURSES FROM AFRICA

Studia Universitatis Babeş-Bolyai. Studia Europaea, 2019
African voices and experiences have been erased from the canon of mainstream IR theory, and even in well-intentioned accounts that take the power dynamics between the developed and underdeveloped world into account. This is a product of a worldview that
Sandy AFRICA, Suzanne GRAHAM
doaj   +1 more source