Results 171 to 180 of about 1,247,857 (307)

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Inspiring hope, confronting hopelessness: healthcare experiences of Black/African American pregnant and post-partum women and healthcare workers in Detroit, Michigan, U.S.A. [PDF]

BMC Pregnancy Childbirth
Kaljee L, Dankerlui D, Pach A, Davidson B, Opara IN, Reyes L, MacLean L.   +6 more
europepmc   +1 more source

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Experiences of Food Insecurity During Pregnancy in High-Income Countries: A Meta-Synthesis of Qualitative Studies. [PDF]

J Hum Nutr Diet
Scott S, Nguyen G, Bell Z, Clark L, van der Pligt P, McKay FH, Zinga J, Heslehurst N.   +7 more
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Excerpt from Black Land: Imperial Ethiopianism and African America (2019)

Journal of Transnational American Studies, 2020
Nadia Nurhussein
doaj   +1 more source

A Community-Engaged Approach for Assessment of Cortisol Dynamic Range and Multilevel Chronic Stress in African Americans: FAITH! Heart Health+ Ancillary Study. [PDF]

J Particip Med
Ortiz R, Joseph J, Johnson MP, Moen L, Lalika M, Jones C, Bancos I, Cooper LA, Hayes SN, Patten CA, Brewer LC.   +10 more
europepmc   +1 more source

The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin

Annals of Neurology, EarlyView.
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth, Björn‐Hergen Laabs, Sebastian Sendel, Inke R. König, Amke Caliebe, Alastair J. Noyce, Laurel A. Screven, Soraya Bardien, Matthew Farrer, Faycel Hentati, Rim Amouri, Christine Klein, Samia Ben Sassi, Joanne Trinh, Global Parkinson's Genetics Program (GP2)   +14 more
wiley   +1 more source

Pathways to participation - a scoping review outlining barriers and enablers to participation in dementia research. [PDF]

J Prev Alzheimers Dis
Duffner LA, Moradi-Bachiller S, Gove D, Diaz-Ponce AM, Bradshaw A, Georges J.   +5 more
europepmc   +1 more source

Effect of Temperature and Atmosphere on Agglomeration of Bed Particles in a Bubbling Fluidised Bed Burning Na‐Enriched Coal

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Agglomeration of bed materials during circulating fluidised bed (CFB) combustion or gasification of high‐alkali fuel is a practical challenge in industrial practice. This work investigates experimentally the effect of temperatures (700°C–900°C) and atmosphere (air equivalence ratios 1.61–0.53) on agglomeration in a lab‐scale bubbling fluidised
Zipeng Guo, Jianbo Li, Xiaofei Long, Quanhai Wang, Xiaofeng Lu   +4 more
wiley   +1 more source