Results 41 to 50 of about 675,585 (278)

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.

open access: yesPLoS Genetics, 2014
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies ...
Maggie C Y Ng   +90 more
doaj   +1 more source

Perspectives on the impact of painful diabetic peripheral neuropathy in a multicultural population

open access: yesClinical Diabetes and Endocrinology, 2017
Background Since few studies have characterized painful diabetic peripheral neuropathy (pDPN) symptoms in multicultural populations, this study fielded a survey to better understand pDPN and its impact in African-American, Caucasian, and Hispanic ...
Martin Eichholz   +6 more
doaj   +1 more source

African Americans and Opportunity [PDF]

open access: yes, 2006
Despite considerable progress over the last several decades, African Americans continue to face many barriers to opportunity Find out how African Americans are faring along our 6 dimensions of ...

core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Common variation in vitamin D pathway genes predicts circulating 25-hydroxyvitamin D Levels among African Americans. [PDF]

open access: yesPLoS ONE, 2011
Vitamin D is implicated in a wide range of health outcomes, and although environmental predictors of vitamin D levels are known, the genetic drivers of vitamin D status remain to be clarified.
Lisa B Signorello   +10 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

ApoE genotype affects allele-specific apo[a] levels for large apo[a] sizes in African Americans: the Harlem-Basset Studys⃞

open access: yesJournal of Lipid Research, 2007
The genetic variability of apolipoprotein E (apoE) influences plasma lipoprotein levels, and allele frequencies differ between African Americans and Caucasians.
Erdembileg Anuurad   +4 more
doaj   +1 more source

Institutional Racism and Black Resistance as Portrayed through Images and Narratives in American Graphic Novels

open access: yesMozaik Humaniora, 2020
For centuries, racial discrimination and injustice have resulted in the struggle of African Americans to resist racial inequality. Nevertheless, their struggle has never been easy since racism against African Americans has long been institutionalized. In
Titien Diah Soelistyarini   +2 more
doaj   +1 more source

Poverty, Race, and Community Policing in Buffalo [PDF]

open access: yes, 2015
The region’s inequality has dramatic effects in every aspect of life, and the criminal justice system is no exception. As PPG documented in its 2013 report, Alarming Disparities, African-Americans account for 14% of Erie County’s population but 43% of ...

core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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