Results 61 to 70 of about 675,585 (278)

4355 Impact of Demographic & Racial Differences on DNA Repair Capacity in Lung Cancer

Journal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: Lung cancer is the leading cause of cancer-related mortality in the United States for both men and women. African Americans are disproportionately affected with lung cancer, having higher incidence and mortality rates compared to ...
Francesca Christina Duncan, Catherine Sears, Nawar Al Narallah, Ahmad Al-Hader   +3 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

New Discovery: Robert S. Duncanson’s Ruins of Carthage (1845)

Panorama, 2021
By depicting a celebrated African site singled out by African Americans at an 1843 state convention in Michigan as proof that “we are worthy of the name of American citizens,” as asserted by Committee Chairman William Lambert, Duncanson was expressing ...
Theresa Leininger-Miller
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Race modifies the relationship between cognition and Alzheimer’s disease cerebrospinal fluid biomarkers

Alzheimer’s Research & Therapy, 2017
Background African Americans have been reported to have a higher prevalence of Alzheimer’s disease (AD) than Caucasians, but etiology-specific AD biomarkers have not been systematically analyzed in older African Americans.
Jennifer C. Howell, Kelly D. Watts, Monica W. Parker, Junjie Wu, Alexander Kollhoff, Thomas S. Wingo, Cornelya D. Dorbin, Deqiang Qiu, William T. Hu   +8 more
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

The influence of race and ethnicity on becoming a human subject: Factors associated with participation in research

Contemporary Clinical Trials Communications, 2017
Inroduction: The purpose of this study was to explore factors associated with willingness of African Americans and Latinos to participate in biomedical and public health research and to delineate factors that influence the decision to become a human ...
Mary A. Garza, PhD, Sandra Crouse Quinn, PhD, Yan Li, PhD, Luciana Assini-Meytin, MS, Erica T. Casper, MA, Craig S. Fryer, DrPH, James Butler, III, DrPH, Natasha A. Brown, PhD, Kevin H. Kim, PhD, Stephen B. Thomas, PhD   +9 more
doaj   +1 more source

Racial disparities in the prevalence and control of hypertension among a cohort of HIV-infected patients in the southeastern United States. [PDF]

PLoS ONE, 2018
BACKGROUND:African Americans are disproportionately affected by both HIV and hypertension. Failure to modify risk factors for cardiovascular disease and chronic kidney disease such as hypertension among HIV-infected patients may attenuate the benefits ...
Greer A Burkholder, Ashutosh R Tamhane, Monika M Safford, Paul M Muntner, Amanda L Willig, James H Willig, James L Raper, Michael S Saag, Michael J Mugavero   +8 more
doaj   +1 more source

Native Americans/African Americans

, 2015
This issue brief examines aspects of the historical relationship between Native Americans and African Americans in the United States, in particular the enduring wounds originating in enslavement and intermarriage.
Blackwood, Emma Kate Frances, Smith, Raymond Arthur   +1 more
openaire   +2 more sources

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source