Evidence of Intragenic Recombination in African Horse Sickness Virus [PDF]
Intragenic recombination has been described in various RNA viruses as a mechanism to increase genetic diversity, resulting in increased virulence, expanded host range, or adaptability to a changing environment.
Harry G. Ngoveni +2 more
doaj +8 more sources
African Horse Sickness Virus Serotype 1 on Horse Farm, Thailand, 2020 [PDF]
To investigate an outbreak of African horse sickness (AHS) on a horse farm in northeastern Thailand, we used whole-genome sequencing to detect and characterize the virus. The viruses belonged to serotype 1 and contained unique amino acids (95V,166S, 660I
Napawan Bunpapong +11 more
doaj +5 more sources
Pathological features of African horse sickness virus infection in IFNAR−/− mice [PDF]
African Horse Sickness (AHS) is a vector-borne viral disease of equids. The disease can be highly lethal with mortality rates of up to 90% in non-immune equine populations.
Luke M. Jones +5 more
doaj +6 more sources
Characterising Non-Structural Protein NS4 of African Horse Sickness Virus. [PDF]
African horse sickness is a serious equid disease caused by the orbivirus African horse sickness virus (AHSV). The virus has ten double-stranded RNA genome segments encoding seven structural and three non-structural proteins.
Lizahn Zwart +3 more
doaj +7 more sources
Safety and immunogenicity of plant-produced African horse sickness virus-like particles in horses [PDF]
African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced in South Africa, risks associated with these
Susan J. Dennis +7 more
doaj +8 more sources
Development of Differentiating Infected from Vaccinated Animals (DIVA) Real-Time PCR for African Horse Sickness Virus Serotype 1 [PDF]
African horse sickness (AHS) is a highly infectious and often fatal disease caused by 9 serotypes of the orbivirus African horse sickness virus (AHSV).
Yifan Wang +11 more
doaj +2 more sources
Investigating the Role of African Horse Sickness Virus VP7 Protein Crystalline Particles on Virus Replication and Release [PDF]
African horse sickness is a deadly and highly infectious disease of equids, caused by African horse sickness virus (AHSV). AHSV is one of the most economically important members of the Orbivirus genus. AHSV is transmitted by the biting midge, Culicoides,
Shani Bekker +3 more
doaj +2 more sources
Clinical, Virological and Immunological Responses after Experimental Infection with African Horse Sickness Virus Serotype 9 in Immunologically Naïve and Vaccinated Horses [PDF]
This study described the clinical, virological, and serological responses of immunologically naïve and vaccinated horses to African horse sickness virus (AHSV) serotype 9.
Manuel Durán-Ferrer +10 more
doaj +2 more sources
Construction and Immunogenicity Evaluation of a Recombinant Fowlpox Virus Expressing VP2 Gene of African Horse Sickness Virus Serotype 1 [PDF]
African horse sickness (AHS) is a lethal vector-borne disease caused by African horse sickness virus (AHSV) and represents a major threat to equine health and the horse industry.
Xiaohua Ma +9 more
doaj +2 more sources
Culicoides biting midges (Diptera: Ceratopogonidae) feeding on donkeys in the United Kingdom, with reference to the risk of transmission and persistence of African horse sickness virus. [PDF]
Culicoides biting midges were collected at a donkey sanctuary in the United Kingdom using UV light‐suction traps. Culicoides were found in abundance and all specimens were identified to species level. Blood‐feeding on donkeys was confirmed by polymerase chain reaction (PCR) and sequencing of host bloodmeals. Donkeys could play a significant role in the
Langlands Z +3 more
europepmc +2 more sources

