Results 31 to 40 of about 7,548 (190)

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Prevalence of APOL1 Risk Variants in Afro-Descendant Patients with Chronic Kidney Disease in a Latin American Country

International Journal of Nephrology, 2019
Introduction. In Colombia, the genetic background of the populations was shaped by different levels of admixture between Natives, European, and Africans.
Carlos E. Duran, Alejandro Ramírez, Juan G. Posada, Johanna Schweineberg, Liliana Mesa, Harry Pachajoa, Mayra Estacio, Eliana Manzi, Vanessa Aros, Lorena Díaz, Victor H. Garcia   +10 more
doaj   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

Compound‐Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis

Lipids, EarlyView.
ABSTRACT Increasing evidence suggests that dairy consumption may decrease the risk of chronic diseases. However, this association remains unclear due to methodological limitations. As a part of a secondary analysis, we used compound‐specific stable isotope analysis to increase the accuracy of the dairy FA biomarkers (15:0, 17:0), considering that each ...
Camilla Parzanini, Marisa Soo, Shirley Vien, Ji‐Eun Chon, Anthony J. Hanley, Priya Kathirvel, Bohdan Luhovyy, G. Harvey Anderson, Richard P. Bazinet   +8 more
wiley   +1 more source

Cineastas afrodescendientes del siglo XXI, entre diáspora, transnacionalismo y post-racialidad / Filmmakers of African descent in the XXI century, between diaspora, transnationalism and post-raciality

Secuencias, 2016
En los últimos quince años (2001-14), el cine diaspórico afrodescendiente ha crecido, aunque haya sido a través de modalidades diferentes, según los diferentes contextos nacionales.
Leonardo De Francheschi
doaj   +1 more source

Seroprevalence of rodent-borne viruses in Afro-descendent communities in Brazil [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2019
During the Brazilian slavery period, many African migrants were brought to the American continent. Historically, some of these migrants escaped from the Brazilian gold mines and farms to which they had been brought and settled in remote valleys and this was the main mode of resistance to the slavery system.
Jorlan Fernandes, Thayssa Alves Coelho, Renata Carvalho de Oliveira, Livia Stefânia Alves Lima Guedes, Bernardo Rodrigues Teixeira, Alexandro Guterres, Christian Niel, Silvana C. Levis, Barbara Vieira Lago, Ana Rita Coimbra Motta-Castro, Elba Regina Sampaio de Lemos   +10 more
openaire   +5 more sources

Update on Ouratea cidiana Sastre (Ochnaceae), a microendemic species from the Amazon: enlightening the identity and conservation status

Nordic Journal of Botany, EarlyView.
Ouratea cidiana (Ochnaceae) is a microendemic shrub species from the Brazilian Amazonia, occurring along the banks of the Trombetas River and restricted to the Cachoeira Porteira region, in western Pará State. Since the original collection nearly forty years ago, no additional records have been made, which is concerning given the continuous decline in ...
Clebiana de Sá Nunes, Mayara Dias Caldas, Fúvio Rubens Oliveira‐da‐ Silva, Anna Luiza Ilkiu‐ Borges, André dos Santos Bragança Gil   +4 more
wiley   +1 more source

Prediciendo el desempeño académico según el entorno familiar de los estudiantes: evidencia para Colombia usando árboles de clasificación [PDF]

, 2019
Family environment, parental economic and social conditions influence students’ academic performance. However, in Colombia, research and methods that have been used to study these variables are rather limited.
García-González, Juan D., Skrita, Anastasija   +1 more
core   +2 more sources

HLA-E polymorphisms in an Afro-descendant Southern Brazilian population [PDF]

Human Immunology, 2013
HLA-E is a non-classical I (Ib) gene which has limited polymorphism and low levels of tissue expression. Currently, 11 alleles are described in the literature with only three protein products. In the present study we investigated HLA-E gene variations at exons 2 and 3 and calculated allele, genotype and haplotype frequencies in a sample of 152 ...
Luana, Carvalho dos Santos, Luciane Viater, Tureck, Pryscilla Fanini, Wowk, Sibelle Botogosque, Mattar, Georgia Fernanda, Gelmini, João Carlos Marques, Magalhães, Maria da Graça, Bicalho, Valéria Maria Munhoz Sperandio, Roxo   +7 more
openaire   +2 more sources

Where Have I Seen You Before? Networks, Trust and Reciprocity as a Source of Collaboration in the Public Service

Public Administration and Development, EarlyView.
ABSTRACT Although some studies focus on how bureaucrats' interactions with one another affect performance, they rarely focus on why these public servants collaborate. Bureaucrats' collaboration matters because it can significantly contribute to achieving policy goals.
Nathalie Mendez
wiley   +1 more source