Results 41 to 50 of about 13,631,366 (252)

Development over time in point-of-care test use in Danish daytime and out-of-hours general practice: a register-based study

Scandinavian Journal of Primary Health Care, 2023
Objective To describe the development over time of the use of C-reactive protein (CRP) and rapid streptococcal detection test (RADT) point-of-care tests (POCT) in Danish general practice and to explore associations between patient characteristics and ...
Niels Kjær, Malene Plejdrup Hansen, Henrik Schou Pedersen, Morten Bondo Christensen, Linda Huibers   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Development and evaluation of an “emergency access button” in Danish out-of-hours primary care: a study protocol of a randomized controlled trial

BMC Health Services Research, 2017
Background Out-of-hours (OOH) health care for acute medical problems is often challenged by long waiting time for callers in need of advice and triage.
J. F. Ebert, L. Huibers, F. K. Lippert, B. Christensen, M. B. Christensen   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Association of Off‐Hour Admission With Treatment Delay and Unfavorable Outcomes in Patients With Stroke: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Despite numerous efforts to reduce the elevated mortality rate of patients with stroke admitted to the hospital during weekends or nights, it remains unclear whether the off‐hour treatment has been improved.
Yiling Lou, Shiqi Wang, Hengchang Wang, Yulin Xie, Yan Guo, Linlin Wang, Rongxia Zhong, Zuxun Lu, Fujian Song, Furong Wang, Qingqing Jiang, Shiyi Cao   +11 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The accuracy and feasibility of respiratory rate measurements in acutely ill adult patients by GPs: a mixed-methods study

BJGP Open, 2022
Background: Tachypnoea in acutely ill patients can be an early sign of a life-threatening condition such as sepsis. Routine measurement of the respiratory rate by GPs might improve the recognition of sepsis. Aim: To assess the accuracy and feasibility of
Feike J Loots, Irma Dekker, Ruo Chen Wang, Arthur RH van Zanten, Rogier M Hopstaken, Theo JM Verheij, Paul Giesen, Marleen Smits   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Migrants’ motives and expectations for contacting out-of-hours primary care: a survey study

BMC Family Practice, 2017
Background Migrants are more likely to use out-of-hours primary care, especially for nonurgent problems. Their motives and expectations for help-seeking are as yet unknown.
Ellen Keizer, Peter Bakker, Paul Giesen, Michel Wensing, Femke Atsma, Marleen Smits, Maria van den Muijsenbergh   +6 more
doaj   +1 more source

After-hours care models in leading countries [PDF]

Pediatric Emergency Medicine Journal, 2017
After-hours care (AHC) provides medical care after the regular weekday work hours of clinics. In Korea, data from the National Emergency Department Information System showed that approximately 40% of the pediatric patients need AHC.
Mi Jin Kim, Young Ho Kwak
doaj   +1 more source