Structure-Activity Relationships for 5'' Modifications of 4,5-Aminoglycoside Antibiotics. [PDF]
Multiple modifications (X) are tolerated at the ribofuranosyl 5‐position in neomycin B and the apralogs, but only amine‐based derivatives are active in the paromomycins, propylamycins and ribostamycins. This is discussed in terms of total amino group count and the ring 1 functionality, amino or hydroxy, with amino groups at the 6’‐ and 7’‐positions in ...
Quirke JCK +8 more
europepmc +2 more sources
Weed Management During Pasture Establishment
SS-AGR-287, a 2-page fact sheet by Brent Sellers, Jason Ferrell, Joao Vendramini, and Yoana Newman, details techniques for chemical weed control prior to and during pasture establishment in Florida.
Brent Sellers +3 more
doaj +7 more sources
Weed Management during Pasture Establishment
This publication details techniques for chemical weed control prior to and during pasture establishment and is intended for county Extension faculty as well as owners and managers of grazing lands.
Brent A. Sellers +4 more
doaj +2 more sources
Localized TWIST1 and TWIST2 basic domain substitutions cause four distinct human diseases that can be modeled in Caenorhabditis elegans. [PDF]
Twist transcription factors, members of the basic helix-loop-helix family, play crucial roles in mesoderm development in all animals. Humans have two paralogous genes, TWIST1 and TWIST2, and mutations in each gene have been identified in specific ...
Kim S +15 more
europepmc +3 more sources
Variation in TP63 is Associated with Lung Adenocarcinoma in the UK Population [PDF]
Background: Variation at TP63 has recently been shown to be associated with lung adenocarcinoma in the Asian population. Methods: To investigate how this finding translates to the European population we compared the genotypes of SNPs ...
Athena Matakidou +5 more
core +1 more source
Design Thinking - Une méthode au service de l’innovation
International audienceLe Design Thinking est une méthode d’innovation incrémentale, centrée sur l’utilisateur. En pratique, il existe différentes approches du Design Thinking.Cet article présente une grille de lecture de ces différentes approches, ainsi ...
Aurélien FERRY +2 more
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The Material and Social Costs of Roman Warfare in the Third and Second Centuries B.C.E. [PDF]
This dissertation examines the causes of Roman military success and expansion beyond Italy, focusing on the initial period of expansion from the First Punic War (264 B.C.E.) to the defeat of the Cimbri (101 B.C.E.).
Devereaux, Bret
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Influence Of Conformational Restriction On The Antibacterial Activity And Ribosomal Selectivity Of Aminoglycoside Antibiotics [PDF]
The ever-increasing threat posed by multidrug-resistant infectious bacteria necessitates the development of novel antibiotics. Aminoglycoside antibiotics are growing in interest due to their broad spectrum of activity, lack of known drug related ...
Pirrone, Michael Gabriel
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Addressing The Threat Of Multidrug Resistant Infectious Diseases By Synthesis Of Novel Aminoglycoside Antibiotics [PDF]
The ever-growing increase in multidrug resistant infectious diseases is one of the major cause of human mortality, and there is an inherent need for the development of new antibiotics.
Sati, Girish Chandra
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Molecular taxonomy and population genetics of Lophodermium on Pinus sylvestris in Scotland [PDF]
Endophytes are organism s w hich infect plants asym ptom atically for at least part of their life cycle. The vast m ajority of endophytes are ascom ycete fungi.
Reignoux, Sabrina N.A.
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