Results 41 to 50 of about 160,297 (281)

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort

Journal of International Medical Research, 2020
Objective To describe the clinical features of early-onset androgenetic alopecia (AGA) in a large cohort of Chinese patients. Methods This descriptive study recruited consecutive patients seeking medical treatment for AGA between 1 January 2013 and 30 ...
Qi Ding, Yu-Xuan Xu, Wei-Ling Sun, Jing-Jing Liu, Yu-Yu Deng, Qiao-Fang Wu, Chun-Yu Cao, Lan-Bo Zhou, Yan Lu, Wei-Xin Fan   +9 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Latent iron deficiency in neonates above 34 weeks of gestation

Current Medicine Research and Practice, 2012
Background: Iron deficiency is the most common nutritional deficiency. A high prevalence of iron deficiency is also seen at birth, indicating in utero iron deficiency.
Vivek Choudhury, Arun Soni, Neelam Kler, L M Srivastava, Satish Saluja   +4 more
doaj  

A community-oriented survey on the association between androgenetic alopecia and metabolic syndrome in Chinese people

Frontiers in Medicine, 2022
BackgroundSeveral studies on Caucasians have revealed a positive relationship between androgenetic alopecia (AGA) and metabolic syndrome (MS). However, this correlation varies in different contexts.
Hongliu Zhu, Haijian Guo, Yihong Gao, Yuegang Wei, Tao Mao, Jianqiu Yang   +5 more
doaj   +1 more source

Aggregation‐Controlled Triplet Exciton Regulation Enables Single‐Emitter Color‐Evolving Afterglow

Advanced Science, EarlyView.
A single‐emitter system based on DTP‐R luminophores enables time‐evolving afterglow through aggregation‐regulated excited‐state dynamics. The coexistence and suppression of delayed fluorescence and phosphorescence are controlled via concentration tuning and host‐guest engineering, revealing the RISC origin of delayed fluorescence and enabling ...
Yu Zhang, Zonghang Liu, Gian Albert Alfani, Xilong Wei, Yue Zhang, Ziyu Cui, Yi Lu, Yixuan Chen, Dan Liu, Lin Lu, Zihao Deng, Shuyu Xue, Parvej Alam, Zheng Zhao, Ben Zhong Tang   +14 more
wiley   +1 more source

The AGA's Quality Control

Gastroenterology, 1982
I don't for one second believe that anything I say in the next 15 minutes will stick. You came to Chicago for the course, the symposia, the lectures, and to learn what's new in scholarship and science that applies to your practices and laboratory investigations from the presentations of over 450 abstracts by your peers.
openaire   +2 more sources

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Androgenetic Alopecia in Men: An Update On Genetics

Indian Journal of Dermatology
Androgenetic alopecia (AGA) is defined as the alopecia induced by androgens in genetically predisposed individuals. AGA results in progressive miniaturization of the hair follicles leading to vellus transformation of terminal hair.
Ilakkia Priya Sadasivam, Ravikumar Sambandam, Damayandhi Kaliyaperumal, Jude Ernest Dileep   +3 more
doaj   +1 more source