Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Protocol for a systematic review on routine use of antibiotics for infants less than 6 months of age with growth failure/faltering. [PDF]
BMJ Open, 2022 Imdad A +7 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
A Bimodal Pattern and Age-Related Growth of Intra-Annual Wood Cell Development of Chinese Fir in Subtropical China. [PDF]
Front Plant Sci, 2021 Jiang Y, Zhang X, Chhin S, Zhang J.
europepmc +1 more source
Job flows in Italian SMEs: a longitudinal analysis of growth, size and age [PDF]
, 2010 The paper proposes an empirical investigation of job flows for continuing manufacturing firms in Italy from 1996 to 2004 using high quality data on work forces and other characteristics of the firm.
Corsino, Marco +2 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Age and growth of one of the world's largest carnivorous gastropods, the Florida Horse Conch, Triplofusus giganteus (Kiener, 1840), a target of unregulated, intense harvest. [PDF]
PLoS One, 2022 Herbert GS +8 more
europepmc +1 more source
Treballs de la Societat Catalana de Biologia, 2007 Vascular and degenerative alterations of the central nervous system (CNS) are two of the most common reasons for illness and death in elderly people; they exhibit an age-related GH deficiency that can affect their physiological functions. A study was conducted under chronic in vivo conditions using old Wistar rats, in order to clarify the effects of GH
Ariznavarreta, C. +7 more
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Experimental validation of otolith-based age and growth reconstructions across multiple life stages of a critically endangered estuarine fish. [PDF]
PeerJ, 2021 Xieu W +10 more
europepmc +1 more source