Results 111 to 120 of about 665,732 (266)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Evaluation of Sexual Dimorphism and Age Determination Through Bimastoid Breadth Measurement Using Digital Computed Tomography Images in the Iranian Population

Arab Journal of Forensic Sciences & Forensic Medicine
Individual identification is a critical focus of forensic research, aiming to achieve heightened accuracy in the identification process. Particularly in cases involving fragmented and damaged skeletal remains, sex determination plays a pivotal role.
Fariba Zafari, Amir Javadi, Iman Safari, Mohammad Gholami, Eisareza Zare, Amir Hossein   +5 more
doaj   +1 more source

New Insights into the Diagnosis and Age Determination of Retinal Hemorrhages from Abusive Head Trauma: A Systematic Review. [PDF]

Diagnostics (Basel), 2023
Di Fazio N, Delogu G, Morena D, Cipolloni L, Scopetti M, Mazzilli S, Frati P, Fineschi V.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Radiocarbon Dating of the Historic Derby Boab Tree From Derby, Kimberley, Australia

Studia Universitatis Babes-Bolyai Chemia
The paper presents the AMS (accelerator mass spectrometry) radiocarbon dating investigation of the historic Derby Boab Tree from Derby, Kimberley, Australia.
Adrian PATRUT, Laszlo RAKOSY, Karl F. REDEN, von   +2 more
doaj   +1 more source

State-of-Art in the Age Determination of Venous Thromboembolism: A Systematic Review. [PDF]

Diagnostics (Basel), 2021
Di Fazio N, Delogu G, Ciallella C, Padovano M, Spadazzi F, Frati P, Fineschi V.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Comment on Fetal Gestational Age Determination Using Ultrasound Placental Thickness. [PDF]

J Med Ultrasound, 2022
Mungmunpuntipantip R, Wiwanitkit V.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Correction to: 'Age determination in echinoderms: first evidence of annual growth rings in holothuroids' 2022 by Sun et al. [PDF]

Proc Biol Sci, 2022
Sun J, Hamel JF, Gianasi BL, Mercier A.
europepmc   +1 more source