Results 101 to 110 of about 3,358,063 (266)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hotărârea Curţii Europene a Drepturilor Omului în cauza Deaconu împotriva României [PDF]

Drepturile Omului, 2019
The present case shows that all courts should bear in mind that nobody should be discriminated if they are in a similar situation, especially if there are no clear grounds for a different treatment.
Andreea Moroianu
doaj  

Brain predicted age difference mediates pain impact on physical performance in community dwelling middle to older aged adults. [PDF]

Geriatr Nurs, 2023
Peterson JA, Johnson A, Nordarse CL, Huo Z, Cole J, Fillingim RB, Cruz-Almeida Y.   +6 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Brain-Predicted Age Difference Moderates the Association Between Muscle Strength and Mobility. [PDF]

Front Aging Neurosci, 2022
Vaughan BA, Simon JE, Grooms DR, Clark LA, Wages NP, Clark BC.   +5 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Factors Influencing Change in Brain-Predicted Age Difference in a Cohort of Healthy Older Individuals. [PDF]

J Alzheimers Dis Rep, 2022
Wrigglesworth J, Harding IH, Ward P, Woods RL, Storey E, Fitzgibbon B, Egan G, Murray A, Shah RC, Trevaks RE, Ward S, McNeil JJ, Ryan J, ASPREE investigator group.   +13 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Brain-predicted age difference is associated with cognitive processing in later-life. [PDF]

Neurobiol Aging, 2022
Wrigglesworth J, Yaacob N, Ward P, Woods RL, McNeil J, Storey E, Egan G, Murray A, Shah RC, Jamadar SD, Trevaks R, Ward S, Harding IH, Ryan J, ASPREE investigator group.   +14 more
europepmc   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source