Results 131 to 140 of about 3,358,063 (266)

Nonagenarians and Octogenarians Undergoing THA and TKA: A 10-Year Age Difference Increases Rates of In-Hospital Complications But Does Not Affect 90-Day Outcomes. [PDF]

HSS J, 2022
Fleisher I, Ong CB, Chiu YF, Krell E, Cushner FD, Gausden E, Boettner F, Gonzalez Della Valle A.   +7 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Using age difference and sex similarity to detect evidence of sibling influence on criminal offending. [PDF]

Psychol Med, 2022
Mikkonen J, Savolainen J, Aaltonen M, Martikainen P.   +3 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Age and Fibromyalgia as Moderators of the Relationships Between Pain and Loneliness: A Longitudinal Study in Patients with Chronic Pain

Journal of Pain Research
Chih-Hsun Wu,1,2 Wei-Han Chou,3 Hao-Han Yang,2 Tung Lin,2 Yi-Hsun Long,2,4 Chi-Cheng Yang,1,2 Wei-Zen Sun,3 Chih-Peng Lin3 1Department of Psychology, National Chengchi University, Taipei, Taiwan; 2Clinical Psychology Center, National Taiwan University ...
Wu CH, Chou WH, Yang HH, Lin T, Long YH, Yang CC, Sun WZ, Lin CP   +7 more
doaj  

Effect of Donor-Recipient Age Difference on Liver Transplant Outcomes. [PDF]

Transplant Direct
Shirini K, Al Ramlawi A, Longchamp A, Bhati C, Meier RPH.   +4 more
europepmc   +1 more source

Kidney age - chronological age difference (KCD) score provides an age-adapted measure of kidney function. [PDF]

BMC Nephrol, 2021
Campbell DJ, Coller JM, Gong FF, McGrady M, Boffa U, Shiel L, Liew D, Stewart S, Owen AJ, Krum H, Reid CM, Prior DL.   +11 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Age difference in the combined effect of soda drinks consumption and body adiposity on hyperuricaemia in US adults. [PDF]

Public Health Nutr, 2021
Lin WT, Kao YH, Lin HY, Li MS, Luo T, Fritz JM, Seal DW, Lee CH, Hu CY, Tseng TS.   +9 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source