Results 71 to 80 of about 2,561,520 (316)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Two Decades of Insights: Comprehensive Histopathological and Epidemiological Analysis of Conjunctival Tumors

open access: yesLife
This study analyzed 2102 conjunctival lesions excised between 1981 and 2003 at a single tertiary center in Serbia, with the aim of evaluating their histopathological characteristics, anatomical localization, and demographic distribution.
Dolika D. Vasović   +11 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Frequency and characteristics of patients with myocardial infarction with ST elevation in Subotica [PDF]

open access: yesABC: časopis urgentne medicine
Introduction: Myocardial infarction (MI) remains a leading cause of mortality and disability worldwide. This study aimed to analyze the incidence of MI in Subotica during 2023, with particular focus on age and gender distribution as well as seasonal ...
Gavrilović Nikola   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Age-group distribution.

open access: yes
Age-group distribution in terms of age groups provided in the Autonomic Aging dataset [10]. The age groups span a range from 18 to 92 years, where the majority of patients are between 20 to 50 years old.
Gabriel Ott (18349361)   +4 more
core   +1 more source

Age-specific HPV type distribution of invasive cervical cancer cases by screening status in last 10 years.

open access: yes, 2023
Age-specific HPV type distribution of invasive cervical cancer cases by screening status in last 10 years.
Carina Eklund (422178)   +6 more
core   +1 more source

Clinical outcomes of personalized blastocyst embryo transfer after endometrial receptivity analysis: A multicenter, retrospective cohort study

open access: yesReproductive Medicine and Biology, 2023
Purpose To evaluate clinical outcomes after endometrial receptivity analysis (ERA). Methods This was a multicenter, retrospective cohort study involving 861 women who underwent ERA testing at certified fertility clinics in Japan, and who received ...
Yuya Takeshige   +13 more
doaj   +1 more source

Age distributions in stochastically dividing populations [PDF]

open access: yesJournal of Theoretical Biology, 1968
Abstract Let N(a, t) be the number of cells of age less than a in a population of mortal, dividing cells at time t . If probabilities of death and division are given as functions of cell age, then N(a, t) is a random variable. The mean and variance of this random variable have the following asymptotic behavior as functions of time: if the ...
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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