Results 121 to 130 of about 1,997,641 (297)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Life lived and left: Carey's equality

Demographic Research, 2009
In a stationary population, age composition and the distribution of remaining lifespans are identical. This equivalence can be used to estimate age structure if information is available on time to death.
James W. Vaupel
doaj  

The Who’s, What’s, and “Y”s: Y Sex Chromosome Loss and Methylation for Analysis in Male Aging and Mortality and Forensic Science Applications

Forensic Sciences
The Y chromosome plays a crucial role in understanding the overall landscape of male health. Incorporating the Y chromosome into genomic and epigenomic research may elucidate the male-specific mechanisms behind aging and the pathogenesis of certain ...
Mira Sapozhnikov, Francisco Medina-Paz, María Josefina Castagnola, Sara C. Zapico   +3 more
doaj   +1 more source

Forensic Age Estimation.

Deutsches Arzteblatt international, 2017
Forensic age estimation is requested by courts and other government authorities so that immigrants whose real age is unknown should not suffer unfair disadvantages because of their supposed age, and so that all legal procedures to which an individual's age is relevant can be properly followed.
Andreas, Schmeling, Reinhard, Dettmeyer, Ernst, Rudolf, Volker, Vieth, Gunther, Geserick   +4 more
openaire   +1 more source

Regional age structure and economic growth: an econometric study for German regions [PDF]

This paper analyses the impact of the regional age structure on growth of German regions. Based on a neoclassical growth model an augmented Solow model was derived and estimated in a spatial econometric approach.
Brunow, Stephan, Hirte, Georg
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Annular bone growth in phalanges of five Neotropical Harlequin Frogs (Anura: Bufonidae: Atelopus)

Phyllomedusa: Journal of Herpetology, 2012
Skeletochronological studies were conducted on museum specimensrepresenting five species of the highly threatened Neotropical genus Atelopus (Bufonidae).We detected annular bone growth (expressed as lines of arrested growth [LAGs]) patternsin each ...
Erik Lindquist, Michael Redmer, Emily Brantner   +2 more
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Bone Age Estimation of Chinese Han Adolescents’s and Children’s Elbow Joint X-rays Based on Multiple Deep Convolutional Neural Network Models

Fayixue Zazhi
ObjectiveTo explore a deep learning-based automatic bone age estimation model for elbow joint X-ray images of Chinese Han adolescents and children and evaluate its performance.MethodsA total of 943 （517 males and 426 females） elbow joint frontal view X ...
LI Dan-yang, ZHOU Hui-ming, WAN Lei, LIU Tai-ang, LI Yuan-zhe, WANG Mao-wen, WANG Ya-hui   +6 more
doaj   +1 more source