Results 161 to 170 of about 1,986,358 (294)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Dental age estimation in children and adolescents with amelogenesis imperfecta. [PDF]

BMC Oral Health
Saygili S, Tasyapan SA, Cameriere R, Cakir Karabas H, Koruyucu M, Kasimoglu Y.   +5 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Histological and Immunohistochemical Biomarkers for Wound Age Estimation in Human Skin: A Systematic Review. [PDF]

Cureus
Ahmed AE, Aljohani WF, Moafa AK, Hattan FA, Altalhi YA, Alsulamy NS, Albalawi ZM, Aldhubayi FM, Alatawi AA, Alqahtani NK.   +9 more
europepmc   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Sonographic Assessment of Fetometric Parameters in Pigs of Different Prolific Genotypes for Gestational Age Estimation. [PDF]

Animals (Basel)
Janelt F, Kauffold J, Sigmarsson HL, Hamedy A, Riehn K, Koethe M, Altemeier J, Rolzhäuser PM.   +7 more
europepmc   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Epigenetic Age Estimation for Hawaiian False Killer Whales (Pseudorca crassidens) in the Absence of 'Known-Age' Individuals. [PDF]

Mol Ecol Resour
Martien KK, Baird RW, Robertson KM, Kratofil MA, Mahaffy SD, West KL, Chivers SJ, Archer FI.   +7 more
europepmc   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Less-invasive age estimation using hair based on DNA methylation in brown bears. [PDF]

Sci Rep
Nakamura S, Yamazaki J, Matsumoto N, Hagino K, Sakamoto H, Yamanaka M, Nakanishi M, Jimbo M, Yanagawa Y, Ito H, Tsubota T, Shimozuru M.   +11 more
europepmc   +1 more source