Results 1 to 10 of about 8,761,882 (367)

Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools

open access: yesFrontiers in Chemistry, 2022
Protein aggregation into highly ordered, regularly repeated cross-β sheet structures called amyloid fibrils is closely associated to human disorders such as neurodegenerative diseases including Alzheimer’s and Parkinson’s diseases, or systemic diseases ...
Isabelle Landrieu   +9 more
doaj   +1 more source

Differential transcript usage unravels gene expression alterations in Alzheimer’s disease human brains

open access: yesnpj Aging and Mechanisms of Disease, 2021
Alzheimer’s disease (AD) is the leading cause of dementia in aging individuals. Yet, the pathophysiological processes involved in AD onset and progression are still poorly understood. Among numerous strategies, a comprehensive overview of gene expression
Diego Marques-Coelho   +6 more
doaj   +1 more source

Correlation of the radial inclination angle in the distal part of the radius with the volar cortical angle and age-related changes of these angles [PDF]

open access: yesVojnosanitetski Pregled, 2023
Background/Aim. The radial inclination (RI) and volar cortical (VC) angle values used in the treatment of radial distal end fractures may vary depending on factors such as the age and gender of the patient.
Yazıbaşı Hüsniye Tuğba   +5 more
doaj   +1 more source

Age As a Risk Factor [PDF]

open access: yesMedical Clinics of North America, 2012
The risk of developing cardiovascular disease (CVD) is generally dependent on the presence or absence of traditional risk factors. Age is a well-known traditional risk factor, generally considered nonmodifiable. This review discusses the common use of individual age in prediction of CVD incidence using different risk scores, whether or not age as a ...
Ravi Dhingra, Ramachandran S. Vasan
openaire   +3 more sources

Prehypertension and hypertension prevalence and risk factors among adult population in Republic of Serbia: A cross-sectional study [PDF]

open access: yesVojnosanitetski Pregled, 2020
Background/Aim. Prehypertension and hypertension are an important public health problem worldwide and although they can be modified, they are often a risk for cardiovascular diseases.
Šipetić-Grujičić Sandra   +4 more
doaj   +1 more source

Vascular Aging: Facts and Factors [PDF]

open access: yesFrontiers in Physiology, 2012
"Man is as old as his arteries". This old aphorism has been widely confirmed by epidemiological and observational studies establishing that cardiovascular diseases can be age-related in terms of their onset and progression. Besides, with aging come a number of physiological and morphological changes that alters cardiovascular function and lead to ...
Dantas, A. P.   +2 more
openaire   +5 more sources

Ageing as a Risk Factor for Disease [PDF]

open access: yesCurrent Biology, 2012
Age is the main risk factor for the prevalent diseases of developed countries: cancer, cardiovascular disease and neurodegeneration. The ageing process is deleterious for fitness, but can nonetheless evolve as a consequence of the declining force of natural selection at later ages, attributable to extrinsic hazards to survival: ageing can then occur as
Niccoli, T., Partridge, L.
openaire   +4 more sources

The age factor in Alzheimer’s disease [PDF]

open access: yesGenome Medicine, 2015
Alzheimer's disease is the most common type of dementia, and it is characterized by a decline in memory or other thinking skills. The greatest risk factor for Alzheimer's disease is advanced age. A recent genome-wide study identified a locus on chromosome 17 associated with the age at onset, and a specific variant in CCL11 is probably responsible for ...
Jose Bras, Rita Guerreiro
openaire   +3 more sources

Comparison between three age-stratified cohorts reveals poor prognosis of young patients with tongue carcinoma

open access: yesFrontiers in Oncology, 2022
ObjectivesInvestigation of the prognosis of young patients with tongue carcinoma has been the focus of several recent studies aimed at improving future precision treatment.
Daisuke Baba   +8 more
doaj   +1 more source

ASSOCIATION OF AGE, GENDER, STROKE LOCATION, AND SOCIAL SUPPORT WITH DEPRESSION AND COGNITIVE IMPAIRMENT AFTER STROKE

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To identify depression and cognitive impairment after stroke and analyze association with age, gender, stroke location, and social support. Study Design: A cross-sectional analytical study.
Fazal Ur Rahman Saeed   +2 more
doaj   +1 more source

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