Results 161 to 170 of about 27,530,721 (406)

Stepping over obstacles: Attention demands and aging

open access: yes, 2009
Older adults have been shown to trip on obstacles despite taking precautions to step carefully. It has been demonstrated in dual-task walking that age-related decline in cognitive and attentional mechanisms can compromise postural management. This is yet
Harley, C., Wann, J.P., Wilkie, R.M.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Characteristics of the brood stock of Nesvych intrabreed type of Ukrainian framed and scaly breeds of carp based on the complex of productive and reproductive parameters

open access: yesRibogospodarsʹka Nauka Ukraïni
Purpose. To provide an assessment of the complex of productive and reproductive parameters of the brood stock of the Nesvych intrabreed type of Ukrainian framed and scaly breeds of carp grown in pond conditions of the Polissia zone. Methodology.
H. Kurinenko   +6 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

New Zealand regions, 1986-2001: Population structures [PDF]

open access: yes, 2005
The age structure of a region’s population affects many areas of social and economic development across all sectors, including employment, housing, welfare, health and education.
Baxendine, Sandra   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Epidemiological significance of chronic pharyngitis, nasopharyngitis, sinusitis, and rhinitis in Moscow and the Russian Federation in 1996 to 2009

open access: yesKlinicist, 2014
Objective: to study trends in the incidence and prevalence of chronic pharyngitis, nasopharyngitis, sinusitis, and rhinitis (CPNSR) in differentage groups in Moscow and the Russian Federation (RF) in the period 1996 to 2009.Materials and methods.
A. V. Aksyonova   +2 more
doaj  

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