Results 211 to 220 of about 27,530,721 (406)

Clinical outcomes of chikungunya across age groups: A systematic review. [PDF]

PLoS Negl Trop Dis
Bentvelzen JOM, de Roo AM, Gurgel do Amaral GS, Quist SW, Louwsma T, Vondeling GT, Postma MJ.   +6 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Effects of fatigue on motor unit characteristics in isometric elbow contractions across age groups. [PDF]

Front Neurosci
Kuang H, Qiu F, Liu X, Chen C.
europepmc   +1 more source

Differences in root canal system configuration in human permanent teeth within different age groups

International Endodontic Journal, 2018
J. Martins, R. Ordinola‐Zapata, Duarte Nuno da Silva Marques, H. Francisco, João Caramês   +4 more
semanticscholar   +1 more source

"Tragical-comical-historical-pastoral". Groups and group therapy in the third age [PDF]

, 2007
Garland, Caroline
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Prevalence of hearing loss across age groups in Nepal: a systematic review and meta-analysis protocol. [PDF]

BMJ Open
Bhandari P, Aryal S.
europepmc   +1 more source

Age Groups of Patients with Infectious Venereal Disease, 1957 and 1958. BRITISH CO-OPERATIVE CLINICAL GROUP [PDF]

, 1960

openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Changes in the "U-Shaped" Distribution of Airway Hyperresponsiveness and Characterization of Inflammatory Phenotypes in Different Age Groups. [PDF]

J Asthma Allergy
Hu F, Li XN, Li PQ, Dong CC, Huo RJ, Cheng EJ, Huang M, Tian XR.   +7 more
europepmc   +1 more source