Results 201 to 210 of about 2,696,735 (308)

Maternal BMI, early-life growth, and atopic dermatitis by age 3 years. [PDF]

J Allergy Clin Immunol Glob
Berents FV, Skram MK, Lødrup Carlsen KC, Granum B, Haugen G, Hedlin G, Jonassen CM, Nordlund B, Reiner A, Skjerven HO, Staff AC, Svanes C, Vettukattil R, Söderhäll C, Rehbinder EM.   +14 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Using machine learning to predict the small for gestational age and identify the important predictors: A real-world clinical cohort study in China. [PDF]

PLoS One
Zhang Y, Liu Z, Liu J, Chen J, Zhang X.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Distance to a Drying Saline Lake and Lung Function Development in a Rural Border Cohort of Children.

JAMA Netw Open
Guo F, Kamai EM, Eckel SP, Barahona DD, Olmedo L, Bejarano E, Torres C, Zuidema C, Seto E, Farzan SF, Johnston JE.   +10 more
europepmc   +1 more source

Multidimensional Trends and AI-Based Forecasts of HIV Incidence in Korea, 1985-2024. [PDF]

J Epidemiol Glob Health
Baek S, Cho H, Kim C, Kim Y.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Prediction Models for Early Identification of Overweight and Obese Children-A National Study. [PDF]

Nutrients
Sadaka IL, Grotto I, Sadaka Y, Eilenberg R, Peleg A, Greenberg D.   +5 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Directional and disruptive selection in populations structured by class and continuous ontogeny under incomplete plasticity. [PDF]

PLoS Comput Biol
Weyna A, Mullon C, Lehmann L.
europepmc   +1 more source