Results 71 to 80 of about 2,696,735 (308)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Timing of menarche and pubertal growth patterns using the QEPS growth model

Frontiers in Pediatrics
ObjectivesTo explore the timing of menarche, postmenarcheal growth, and to investigate the impact of various variables on menarcheal age and postmenarcheal and pubertal growth.Study DesignThis longitudinal community population-based study analyzed ...
Jenni Gårdstedt-Berghog, Jenni Gårdstedt-Berghog, Aimon Niklasson, Agneta Sjöberg, A. Stefan Aronson, A. Stefan Aronson, Aldina Pivodic, Aldina Pivodic, Andreas F. M. Nierop, Andreas F. M. Nierop, Kerstin Albertsson-Wikland, Anton Holmgren, Anton Holmgren, Anton Holmgren   +13 more
doaj   +1 more source

Growth model selection for the jumbo squid Dosidicus gigas from the Gulf of California, Mexico

Aquatic Biology, 2014
We analyzed mantle length and age data of the whole ontogenic cycle of the jumbo squid Dosidicus gigas in the Gulf of California, Mexico, to describe its growth pattern.
VY Zepeda-Benitez, E Morales-Bojórquez, J López-Martínez, A Hernández-Herrera   +3 more
doaj   +1 more source

Pediatric growth patterns in youth‐onset type 2 diabetes mellitus: Implications for physiologically‐based pharmacokinetic models

Clinical and Translational Science, 2022
An accurate understanding of the changes in height and weight of children with age is critical to the development of models predicting drug concentrations in children (i.e., physiologically‐based pharmacokinetic models).
Chelsea M. Hosey, Kelsee Halpin, Valentina Shakhnovich, Chengpeng Bi, Brooke Sweeney, Yun Yan, J. Steven Leeder   +6 more
doaj   +1 more source

SPIDER VII - Revealing the Stellar Population Content of Massive Early-type Galaxies out to 8Re [PDF]

, 2012
Radial trends of stellar populations in galaxies provide a valuable tool to understand the mechanisms of galaxy growth. In this paper, we present the first comprehensive analysis of optical-optical and optical-NIR colours, as a function of galaxy mass ...
A. Pasquali, Adelman-McCarthy, Annibali, Aringer, Arnold, Beers, Bergval, Berlind, Bernardi, Bertelli, Bruzual, Bruzual, Caon, Cappellari, Cappellari, Cardelli, Carlberg, Carollo, Cid Fernandes, Clemens, Coccato, Daddi, Davies, Davies, de Jong, de La Rosa, De Vaucoulerus, E. Merlin, Eggen, F. La Barbera, Ferreras, Ferreras, Ferreras, Forbes, G. Bruzual, Gallazzi, Gargiulo, Girardi, González-Pérez, Gorgas, Goudfrooij, Greene, Guo, Hinkley, Hyde, I. Ferreras, Ilbert, Kereš, Kobayashi, Komatsu, Kormendy, Kriek, Kuntschner, Kuntschner, La Barbera, La Barbera, La Barbera, La Barbera, La Barbera, La Barbera, Lackner, Lançon, Larson, Larson, Lawrence, Le Borgne, Lopes, Marigo, Marigo, McClure, Mehlert, Melbourne, Michard, Naab, Oser, Pasquali, Peletier, Pipino, Pipino, R. R. de Carvalho, Rayner, Roche, Roediger, S. Charlot, Saglia, Salpeter, Savoy, Silva, Silva, Spolaor, Suh, Swindle, Sánchez-Blázquez, Sánchez-Blázquez, Tal, Thomas, Tortora, Trujillo, Trujillo, Valdes, van Dokkum, van Dokkum, Warren, Westera, Wise, Worthey, Wu, Zhu, Zibetti   +108 more
core   +2 more sources

Modelling thin film growth in the Ag–Ti system [PDF]

Surface Science, 2019
Abstract Simulations of thin film growth in the Ag–Ti system are presented using molecular dynamics combined with an adaptive kinetic Monte Carlo method (AKMC) with a modified embedded atom potential fit to ab initio data for the surface energies. For the model, atoms are assumed to deposit normally with a kinetic energy of 1–3 eV, with a typical ...
Ying Zhou, Adam L. Lloyd, Roger Smith, Steven D. Kenny   +3 more
openaire   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Effect of spatial pattern of trees on the growth of Norway spruce stand.

Silva Fennica, 1991
The simulation model consists of a method to generate theoretical Norway spruce ( (L.) H. Karst.) stands, and a spatial growth model to predict the growth of these stands.
Pukkala, Timo, Kolström, Taneli
doaj   +1 more source

Modelling the growth of the brown frog (Rana dybowskii) [PDF]

PeerJ, 2018
Well-controlled development leads to uniform body size and a better growth rate; therefore, the ability to determine the growth rate of frogs and their period of sexual maturity is essential for producing healthy, high-quality descendant frogs.
Qing Tong, Xiao-peng Du, Zong-fu Hu, Li-yong Cui, Hong-bin Wang   +4 more
doaj   +2 more sources

Population Modeling of Tumor Growth Curves, the Reduced Gompertz Model and Prediction of the Age of a Tumor [PDF]

, 2019
Quantitative analysis of tumor growth kinetics has been widely carried out using mathematical models. In the majority of cases, individual or average data were fitted. Here, we analyzed three classical models (exponential, logistic and Gom-pertz within the statistical framework of nonlinear mixed-effects modelling , which allowed us to account for ...
Vaghi, Cristina, Rodallec, Anne, Fanciullino, Raphaelle, Ciccolini, Joseph, Mochel, Jonathan, Mastri, Michalis, Ebos, John, Poignard, Clair, Benzekry, Sébastien   +8 more
openaire   +3 more sources