Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Are mobile phone ownership and age of acquisition associated with child adjustment? A 5-year prospective study among low-income Latinx children. [PDF]
Sun X +4 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Subjective age of acquisition norms for 1604 English words by Spanish L2 speakers of English and their relationship with lexico-semantic, affective, sociolinguistic and proficiency variables. [PDF]
Rodriguez-Cuadrado S +6 more
europepmc +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The role of domain-specific practice, handedness and starting age in chess [PDF]
The respective roles of the environment and innate talent have been a recurrent question for research into expertise. This paper investigates markers of talent, environment, and critical period for the acquisition of expert performance in chess ...
Campitelli, G, Gobet, F
core
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The Unemployment Trap Meets the Age-Earning Profile. [PDF]
The relative costs of taking employment or receiving welfare are usually understood through comparisons of a person’s social security entitlements and their wage alternative, known as replacement rates.
Bruce Chapman +3 more
core
A plea for more interactions between psycholinguistics and natural language processing research [PDF]
A new development in psycholinguistics is the use of regression analyses on tens of thousands of words, known as the megastudy approach. This development has led to the collection of processing times and subjective ratings (of age of acquisition ...
Brysbaert, Marc +2 more
core
Hong Kong Chinese character psycholinguistic norms: ratings of 4376 single Chinese characters on semantic radical transparency, age-of-acquisition, familiarity, imageability, and concreteness. [PDF]
Su IF, Yum YN, Lau DK.
europepmc +1 more source

