Results 101 to 110 of about 9,551,929 (358)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Average Peak Age-of-Information Minimization in UAV-Assisted IoT Networks [PDF]

open access: yesIEEE Transactions on Vehicular Technology, 2018
Motivated by the need to ensure timely delivery of information (e.g., status updates) in the Internet-of-Things (IoT) paradigm, this paper investigates the role of an unmanned aerial vehicle (UAV) as a mobile relay to minimize the average peak age-of ...
Mohamed A. Abd-Elmagid   +1 more
semanticscholar   +1 more source

Social determinants of content selection in the age of (mis)information

open access: yes, 2014
Despite the enthusiastic rhetoric about the so called \emph{collective intelligence}, conspiracy theories -- e.g. global warming induced by chemtrails or the link between vaccines and autism -- find on the Web a natural medium for their dissemination ...
A.D.I. Kramer   +25 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

On the age of information for non-preemptive queues in tandem

open access: yesFrontiers in Communications and Networks, 2022
A monitoring system operates over a network of first-come, first-served queues in tandem, in which a source is transmitting its status to a monitor at the end of the tandem.
Clement Kam, Sastry Kompella
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Joint Beamforming, Scheduling, Trajectory, and Transmit Power Optimization in UAV-Assisted ISAC Systems for Information Freshness

open access: yesIEEE Access
In this paper, we consider a system that integrates an unmanned aerial vehicle (UAV) for sensing and communication. The UAV is responsible for communication with multiple users and sensing targets for multiple users.
Yuting He   +5 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Freedom of Speech and the Press in the Information Age [PDF]

open access: yes, 2008
On June 26 -- 27, 2008, more than 130 social studies teachers from across the United States, its territories, Cuba and even Iraq gathered at Georgetown University in Washington, D.C., for the James Madison Symposium conducted in partnership with the ...

core  

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