Results 101 to 110 of about 1,594,214 (312)

Age of Onset of Schizophrenia [PDF]

open access: yesBritish Journal of Psychiatry, 1988
S K, Jayaswal   +2 more
openaire   +2 more sources

The Significance of Age of Onset for Schizophrenia [PDF]

open access: yesSchizophrenia Bulletin, 1992
Age of onset is the single most important characteristic of schizophrenia that could yield clues to its origin. To identify the age of onset, however, the onset of the pathological process must be determined. This process may have more than one component occurring at distinctly different times in the life of an individual.
openaire   +2 more sources

The onset of prolonged glare recovery with age

open access: yes, 1989
The effects of ageing upon the recovery of contrast discrimination following exposure to a bright source of light (glare recovery) were investigated. A total of 65 subjects were tested, with a distribution of ages ranging from 16 to 79 years. Total glare
Michael Collins, Collins, Michael J.
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Strong family history and early onset of schizophrenia: about 2 families in Northern Nigeria

open access: yesThe Pan African Medical Journal, 2016
Schizophrenia is a highly heritable psychotic disorder and high genetic loading is associated with early onset of the disease. The outcome of schizophrenia has also been linked with the age of onset as well as the presence of family history of the ...
Folorunsho Tajudeen Nuhu   +3 more
doaj   +1 more source

The outcome and the influencing factors of the age of onset in post-mortem of chronic bronchitis patients: a retrospective study

open access: yes, 2018
Linyun Zhu,1 Zhenhua Ni,2 Xuming Luo,1 Zhuhua Zhang,1 Shiqiang Wang,1 Ziyu Meng,1 Xiandong Gu,1 Xiongbiao Wang1 1Department of Respiratory Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 2Central Laboratory ...
Ni Z   +7 more
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Pathogenic implications of age of onset in juvenile rheumatoid arthritis [PDF]

open access: yes, 1975
An analysis of age of onset in juvenile rheumatoid arthritis was performed in the last 300 children seen in our clinic. There was a peak age of onset in girls at 1 to 3 years.
Petty, Ross E.   +2 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The rare DRB1*04:08-DQ8 haplotype is the main HLA class II genetic driver and discriminative factor of Early-onset Type 1 diabetes in the Portuguese population

open access: yesFrontiers in Immunology
IntroductionEarly-onset Type 1 diabetes (EOT1D) is considered a disease subtype with distinctive immunological and clinical features. While both Human Leukocyte Antigen (HLA) and non-HLA variants contribute to age at T1D diagnosis, detailed analyses of ...
Iris Caramalho   +10 more
doaj   +1 more source

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