Results 21 to 30 of about 2,699,032 (208)

Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. [PDF]

, 2013
Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
Almasy, Laura, Bauer, Lance, Bierut, Laura, Bucholz, Kathleen, Chorlian, David B, Dick, Danielle, Edenberg, Howard J, Foroud, Tatiana, Goate, Alison, Hesselbrock, Victor, Kang, Sun J, Kramer, John, Kuperman, Sam, Manz, Niklas, Nurnberger, John, Porjesz, Bernice, Rangaswamy, Madhavi, Rice, John, Schuckit, Marc, Tischfield, Jay, Wang, Jen-Chyong   +20 more
core   +2 more sources

Factors affecting marriage in schizophrenia: A cross-sectional study

Journal of Mental Health and Human Behaviour, 2016
Background: Schizophrenia is a chronic psychiatric disorder which has a profound effect on the patient′s life course. Marriage has been shown to be both protective and detrimental to the course of recovery in schizophrenia.
Vikas Deshmukh, Aparna Bhagat, Nilesh Shah, Sushma Sonavane, Avinash Alan Desousa   +4 more
doaj   +1 more source

The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. [PDF]

, 2015
A previous study showed that, in carriers of the apolipoprotein E (APOE) genotype ε3/ε3 or ε3/ε4, the presence of a very long (VL) polyT repeat allele in "translocase of outer mitochondrial membrane 40" (TOMM40) was less frequent in patients with ...
Barohn, R.J., Bettencourt, C., Brady, S., De Bleecker, J., De Paepe, B., Dimachkie, M.M., Fox, Z., Gang, Q., Hanna, M.G., Healy, E., Hilton-Jones, D., Holton, J.L., Houlden, H., Machado, P.M., Mantegazza, R., Mastaglia, F., Moggio, M., Mora, M., Needham, M., Parton, M., Ripolone, M., Shaibani, A., Shieh, P.B., Violano, R., Zanoteli, E., Zanotti, S.   +25 more
core   +1 more source

Trends in Early Sexual Initiation and Its Association with Socio-Environmental Factors among Korean Adolescents

Children, 2023
There has been no research on the trends in early sexual initiation associated with socio-environmental factors in Korea. This study aimed to examine the trends of early sexual initiation with various socio-environmental factors among adolescents.
Dong-Hee Ryu
doaj   +1 more source

Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]

, 2017
INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy, Germinaro, Matthew, Weiss, Sivan, Zangrilli, James   +3 more
core   +2 more sources

Differences in Clinical and Dietary Characteristics, Serum Adipokine Levels, and Metabolomic Profiles between Early- and Late-Onset Gout

Metabolites, 2021
This study aimed to identify differences in clinical and dietary characteristics, serum adipokine levels, and metabolomic profiles between early- and late-onset gout.
Young Sun Suh, Hae Sook Noh, Hyun-Jin Kim, Yun-Hong Cheon, Mingyo Kim, Hanna Lee, Hyun-Ok Kim, Sang-Il Lee   +7 more
doaj   +1 more source

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. [PDF]

, 2014
BackgroundThe age at onset of alcohol dependence (AD) is a critical moderator of genetic associations for alcohol dependence. The present study evaluated whether single nucleotide polymorphisms (SNPs) can influence the age at onset of AD in large high ...
Agrawal, Arpana, Almasy, Laura, Bertelsen, Sarah, Bierut, Laura, Bucholz, Kathleen, Budde, John, Dick, Danielle M, Edenberg, Howard J, Foroud, Tatiana, Goate, Alison, Harari, Oscar, Hesselbrock, Victor, Hinrichs, Anthony L, Kapoor, Manav, Kramer, John, Le, Nhung, Nurnberger, John I, Porjesz, Bernice, Rice, John, Schuckit, Marc, Tischfield, Jay, Wang, Jen-Chyong, Wetherill, Leah, Xiaoling, Xuei   +23 more
core   +1 more source

Estimating and comparing the duration of adolescent growth peak in skeletal class I and III subjects using cervical vertebral maturation method

Progress in Orthodontics, 2022
Background Estimating skeletal maturation and growth potential is essential for developing adolescents' best orthodontic treatment plan. The purpose of this study was to compare the duration of adolescent growth peak in subjects of skeletal classes I and
Mohammad H. Naderi, Mina Biria, Soheil Shahbazi, Sina Kousha, Kazem Dalaie, Mohammad Behnaz   +5 more
doaj   +1 more source

Pharmacological And Genetic Reversal Of Age-Dependent Cognitive Deficits Attributable To Decreased Presenilin Function [PDF]

, 2010
Alzheimer\u27s disease (AD) is the leading cause of cognitive loss and neurodegeneration in the developed world. Although its genetic and environmental causes are not generally known, familial forms of the disease (FAD) are attributable to mutations in a
Bell, A. J., Chiorean, S., Choi, C. H., Choi, R. J., Ferreiro, D., Ferrick, N. J., Fortini, M. E., Hinchey, P., Jongens, T. A., Koenigsberg, E., Kollaros, M., Liebelt, D. A., McBride, S. M.J., McDonald, T. V., Nguyen, H. T., Rudominer, R. L., Schoenfeld, B. P., Siwicki, Kathleen King, Sumida, A., Terlizzi, A. M.   +19 more
core   +2 more sources

Age of onset of substance use in patients with dual diagnosis and its association with clinical characteristics, risk behaviors, course, and outcome: A retrospective study

Indian Journal of Psychiatry, 2019
Research Question: Do patients with dual diagnosis (DD) with an early initiation of substance use and subsequent early onset substance use disorder (EOS) differ from those with late onset substance use disorder (LOS) regarding characteristics, sex ...
Bhagyalakshmi Nanjayya Subodh, Swapnajeet Sahoo, Debasish Basu, Surendra Kumar Mattoo   +3 more
doaj   +1 more source