Results 121 to 130 of about 9,799,487 (341)

SOME TYPES OF EARLY IRON AGE KNOBBED RINGS

open access: yesProceedings in Archaeology and History of Ancient and Medieval Black Sea Region, 2023
Статья посвящена некоторым типам колец с выступами раннего железного века центральных, восточных и южных регионов Европы. Рассмотрены кольца с выступами, сгруппированными в розеточку из 2—5 выпуклин, кольца с выступами-ножками, на которых расположены 3—5 шариков, и некоторые кольца с одинарными выступами. В основу работы положена подборка из 188 колец,
openaire   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A comparative study of the growth of the postlarval and juvenile pescadas Plagioscion squamosissimus (HECKEL) and Plagioscion monti (SOARES) in a white water lake of the Central Amazon

open access: yes, 1983
The age of 320 specimen of Plagioscion monti and 280 specimen or P. squamosissimus was determined by means of daily rings on the otoliths. The length of the fish were in the range of 0.4 - 15 cm.
Worthmann, H.
core  

Growth rings, growth ring formation and age determination in the mangrove Rhizophora mucronata [PDF]

open access: yes, 2004
Background and Aims The mangrove Rhizophora mucronata has previously been reported to lack annual growth rings, thus barring it from dendrochronological studies.
Beeckman, H.   +3 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

How does star formation proceed in the circumnuclear starburst ring of NGC 6951?

open access: yes, 2013
Gas inflowing along stellar bars is often stalled at the location of circumnuclear rings, that form an effective reservoir for massive star formation and thus shape the central regions of galaxies. However, how exactly star formation is proceeding within
Emsellem, E.   +5 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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