Results 171 to 180 of about 7,720,905 (351)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Erratum to: aging affects the balance between goal-guided and habitual spatial attention [PDF]
Emily L Twedell +2 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The acceptability of participating in data linkage research: research with older Australians
Stephanie L. Harrison +4 more
doaj +1 more source
Young people aged 10-14 in the youth justice system 2011-12 [PDF]
Summary Young people aged 10-14 are a small but important group in youth justice Despite being a relatively small group, research indicates that young people aged 10-14 in the youth justice system are at risk of becoming chronic, long-term offenders ...
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Planning for Māori Futures: A Scoping Review of Experiences, Priorities and Opportunities for Culturally Informed and Appropriate Aged Care Design. [PDF]
Hikaka JF, August T, Duque M, Kerse N.
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

