Results 61 to 70 of about 7,081,410 (338)
GABRA2 and Alcohol Dependence in College-Aged Students [PDF]
, 2020 GABRA2 and Alcohol Dependence in College-aged Students Abaiz Chaudhri, Depts. of Biology and Chemistry, with Dr. Amy Adkins and Dr. Sally Kuo, Dept. of Psychology Problematic alcohol use and associated consequences is a major problem in college-aged ...
Chaudhri, Abaiz
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
BMC Health Services Research, 2023 Background Lymphoedema is a common, distressing, and debilitating condition affecting more than 200 million people globally. There is a small body of evidence to guide lymphoedema care which underpins several lymphoedema clinical practice guidelines ...
Eric Torgbenu +3 more
doaj +1 more source
An Analysis of College-aged Women’s Personal Relations [PDF]
, 2012 Current communication literature regarding personal relations is limited by its focus on romantic, friendship and friends with benefits relations. To better understand the types of relations college-aged women practice, this study sought to explore (a ...
Hamilton, Amanda E.
core +1 more source
Cell, 2013 Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases.
Carlos López-Otín +4 more
openaire +4 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Incorporating foot assessment in the comprehensive geriatric assessment
BMC Geriatrics, 2021 Background Foot problems are common in older adults and associated with poorer physical function, falls, frailty and reduced quality of life. Comprehensive Geriatric Assessment (CGA), a multidisciplinary process that is considered the gold standard of ...
Rebecca K. Iseli +4 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]
, 2008 An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Erin Lane +7 more
core +1 more source
Optimising nutrition in residential aged care: A narrative review [PDF]
, 2016 In developed countries the prevalence of protein-energy malnutrition increases with age and multi-morbidities increase nutritional risk in aged care residents in particular.
Agarwal, Ekta +3 more
core +2 more sources