Results 81 to 90 of about 7,426,653 (346)

Syphilis among middle-aged female sex workers in China: a three-site cross-sectional study. [PDF]

, 2016
ObjectivesThis study addresses the lack of empirical studies about the epidemic of syphilis among middle-aged female sex workers (FSWs). The objectives of this study were to investigate prevalence of syphilis, and its potential risk factors among middle ...
Dumenci, Levent, Jiang, Baofa, Li, Xiaojing, Liu, Hongjie, Morisky, Donald E, Xu, Yongfang   +5 more
core   +1 more source

Evaluation of a measles vaccine campaign by oral-fluid surveys in a rural Kenyan district: interpretation of antibody prevalence data using mixture models [PDF]

, 2009
We evaluated the effectiveness of a measles vaccine campaign in rural Kenya, based on oral-fluid surveys and mixture-modelling analysis. Specimens were collected from 886 children aged 9 months to 14 years pre-campaign and from a comparison sample of 598
A. BETT, A. VYSE, D. J. NOKES, D. SAMUEL, D. W. G. BROWN, E. A. OKIRO, E. O. OHUMA, Enquselassie, J. ABWAO, Kremer, N. GAY, Nokes, S. WERE, Vyse   +13 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Rehabilitation, reablement, and restorative care approaches in the aged care sector: a scoping review of systematic reviews

BMC Geriatrics
Background Ageing populations are set to drive up demand for aged care services, placing strain on economies funding social care systems. Rehabilitation, reablement, and restorative care approaches are essential to this demographic shift as they aim to ...
Claire Gough, Raechel A. Damarell, Janine Dizon, Paul D.S. Ross, Jennifer Tieman   +4 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Klotho mice: a novel wound model of aged skin. [PDF]

, 2014
BackgroundAs the elderly population continues to expand, it becomes increasingly important to develop treatments to improve wound healing in the elderly.
Yamashita, Ken, Yamauchi, Makoto, Yotsuyanagi, Takatoshi, Young, David M   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Austerity and old-age mortality in England: a longitudinal cross-local area analysis, 2007-2013 [PDF]

, 2016
Objective: There has been significant concern that austerity measures have negatively impacted health in the UK. We examined whether budgetary reductions in Pension Credit and social care have been associated with recent rises in mortality rates among ...
Barr, Ben, Katikireddi, Srinivasa Vittal, Loopstra, Rachel, McKee, Martin, Stuckler, David, Taylor-Robinson, David   +5 more
core   +4 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Interventions to delay functional decline in people with dementia: a systematic review of systematic reviews

BMJ Open, 2016
Objective To summarise existing systematic reviews that assess the effects of non-pharmacological, pharmacological and alternative therapies on activities of daily living (ADL) function in people with dementia.Design Overview of systematic reviews ...
Lindy Clemson, Kate Laver, Maria Crotty, Craig Whitehead, Suzanne Dyer   +4 more
doaj   +1 more source