Results 141 to 150 of about 1,248,790 (310)

Predictors of mortality in very old subjects aged 80 years or over.

, 1993
We studied 318 subjects aged 80 years of over included in the Cardiovascular Study in the Elderly (CASTEL). Some well known risk factors (left ventricular hypertrophy, glucose intolerance, cholesterol, ApoB/ApoA ratio, triglycerides, proteinuria ...
Spolaore P, Di Menza G, Marchioro M, AMBROSIO, GIOVANNI BATTISTA, Ginocchio G, Colangeli G, Mazza A, CASIGLIA, EDOARDO   +7 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Outcomes in patients aged ≥80 years with Hepatopancreaticobiliary (HPB) malignancies

, 2017
Introduction: The elderly are underrepresented in oncological clinical trials, and thus data is limited on treatment practices. The incidence of HPB malignancies is higher in the elderly and data on outcomes, particularly in those aged ≥80 years, is ...
Valle, Juan, Cipriano, Claudia, Wang, Xin, Lewis, Alex, Hubner, Richard, Mcnamara, Mairead; id_orcid, Lamarca, Angela   +6 more
core   +1 more source

Clinical Characteristics and Outcomes of Gastric Cancer Patients Aged over 80 Years: A Retrospective Case-Control Study.

, 2016
Background and aimsThe average human life expectancy is increasing worldwide, thus the proportion of elderly gastric cancer patients is also increasing. In this case-control study, we investigated the clinical and oncologic outcomes of gastric cancer in ...
Ji Yong Ahn, Hee Jung Park (2380813), Jeong Hoon Lee, Kee Don Choi (2658454), Ho June Song (2658475), Gin Hyug Lee (2658481), Ho June Song, Hee Jung Park, Kee Wook Jung, Ji Yong Ahn (594510), Seungbong Han (781387), Hwoon-Yong Jung, Seungbong Han, Gin Hyug Lee, Jin-Ho Kim (535013), Kee Wook Jung (2658472), Kee Don Choi, Jin-Ho Kim, Hwoon-Yong Jung (2658466), Do Hoon Kim (2658469), Jeong Hoon Lee (821420), Do Hoon Kim   +21 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Intensive care of the very old – questioning the relationship between illness severity and the moral imperative to deliver life-saving care

Philosophy, Ethics, and Humanities in Medicine
Background Intensive care provision to very old patients is rapidly growing owing to demographic changes and increasing treatment intensity. However, intensive care carries only questionable benefit for the oldest patients, and many of them die after ...
Gabriele Leonie Schwarz
doaj   +1 more source

Prevalence and management of uncontrolled hypertension in French patients aged over 80 years

, 2014
SummaryBackgroundThe rate of uncontrolled hypertensives aged >80 years is not well known.
Herpin, Daniel, Sosner, Philippe, Ragot, Stéphanie, Dievart, François   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Aid to the elderly person aged 80 and over in the emergency service: perspective of professionals from nursing homes

Introduction: The increase in the average life expectancy of the population has been significantly reflected in the accentuated rate of aging and the increase in the prevalence of chronic diseases, leading to an increase in the number of people aged 80 ...
Esteves, Madalena, Pina, Fernando, Vicente, João, Ribeiro, Olivério, Cunha, Madalena, Cardoso, Joana   +5 more
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Clinical and Statistical Observations on Aged In-patients Hospitalized in the Department of Oral Surgery, Higashi-Nippon-Gakuen University School of Dentistry over the Past 7Years.

, 1987
P(論文)Recently, with the rapid increase in the proportion of aged in the population and with increases in age, the number of senior citizens requesting medical diagnosis at the Departmentof Oral Surgery is increasing. We have conducted a seven year survey,
宮沢, 悦也, 宮田, 雅代, 35474, 35473, 35472, 35471, 北村, 完二, 35470, 35479, 吉川, 保, 35478, 35477, 35476, 35475, 奥村, 一彦, 田中, 毅, 田中, 真樹, 富田, 喜内, 斉藤, 基明, 武田, 充弘, 岡崎, 有志, 35481, 35480, 清水, 信, 村瀬, 博文, 35469, 山下, 徹郎, 35468, 35467, 35466, 22262, 35465, 原田, 尚也, 中川, 徹, 金沢, 正明, 斉藤, 全弘   +35 more
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