Results 231 to 240 of about 5,082,581 (316)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Trends in the Bystander Cardiopulmonary Resuscitation, 2014-2024. [PDF]

Jugan Geongang Gwa Jilbyeong
Kim J.
europepmc   +1 more source

“We’d Love to Match Them, But…”: How Temporary Employment Agencies Understand and Use Race and Ethnicity

, 2011
Meghan M. Sweeney
openalex   +1 more source

Hampshire Authorised Validating Agency [PDF]

, 2002

core  

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Determinants of agency in family planning among marginalized and non-marginalized women: an analysis of the Nepal demographic and health survey 2022. [PDF]

BMC Womens Health
Karki RD, Subedi G, Shrestha B, Lamichhane KD, Karki TM.   +4 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

[Synthesis] Action orientation and enaction: corporeal, linguistic, and cultural mediation in virtual learning environments

TIPA. Travaux interdisciplinaires sur la parole et le langage
Dagmar Abendroth-Timmer
doaj   +1 more source

A Data-Driven Psychiatric Disorder Subtype Defined by Significant Enlarged Ventricles and Cognitive Impairment: A Replication Study. [PDF]

Neuropsychopharmacol Rep
Onitsuka T, Yasuda Y, Ito S, Matsumoto J, Okada N, Yamamoto M, Ohi K, Takahashi T, Kubota M, Hashimoto N, Takano H, Hasegawa N, Okada G, Yoshimura R, Nakagawa S, Yamasue H, Numata S, Hashimoto R.   +17 more
europepmc   +1 more source