Results 61 to 70 of about 107,054 (218)

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

“Looking back” at personal memories on Facebook: Co-constituitive agencies in contemporary remembrance practices

open access: yesJournal of Aesthetics & Culture, 2019
In this paper, we discuss the expression of personal memories in digital media environments. To tackle this issue, we propose a conceptualization that conceives such memories as the outcome of co-constitutive agencies that impact contemporary mnemonic ...
Ana Lúcia Migowski   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Asserting Agency: Meta Vaux Warrick Fuller’s Scrapbook

open access: yesPanorama, 2022
Erika Schneider
doaj   +1 more source

Towards an approach to development as missionary role: the category of personhood as addressed by Amartya Sen?

open access: yesMissionalia: Southern African Journal of Missiology, 2014
This paper is concerned with the role of personhood in development. I will be looking at the extent to which the influential model of development proposed by Amartya Sen does justice to the category of personhood.
Klaasen, John
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Las paradojas de la (in)visibilidad. Trayectorias de vida de las personas transmasculinas en la Argentina contemporánea

open access: yesHorizontes Antropológicos
Resumen Este artículo abordara las trayectorias de vida de las personas transmasculinas en la Argentina contemporánea. En ese marco, el propósito es mostrar las paradojas que atraviesan a estas personas en su proceso de visibilización, con el objeto de ...
Mariana Álvarez Broz
doaj   +1 more source

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