Results 81 to 90 of about 863,194 (303)

Philosophizing the transfixed and the cybernetic

open access: yesEikasía
The article offers a philosophical reflection on today’s transfixed and cybernetic times, where technoscience, digitalization, and artificial intelligence (AI) deeply transform human experience amid a global polycrisis.
Andrés Merejo
doaj   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

open access: yesAdvanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy   +13 more
wiley   +1 more source

Life as Self-Maintenance

open access: yesEthics in Progress
The article constructs the organism as a living being and – unlike an automaton – as an individual concerned with its own self-maintenance, endowed with intrinsic purposiveness, autoregulation, and with an agency of the self as well.
Dieter Wandschneider
doaj   +1 more source

Coteaching social education: An oasis in changing times [PDF]

open access: yes, 2012
With the introduction and continued steady roll-out of the Australian Curriculum, teaching Social Education in 21st Century Australia has become increasingly challenging.
Menzie, Karena, Willis, Linda-Dianne
core   +1 more source

A critical analysis of the conceptualisation of ‘coaching philosophy’ [PDF]

open access: yes, 2016
The aim of this paper was to critically review existing literature relating to, and critically analyse current conceptualisations of, ‘coaching philosophy’.
Althusser L.   +46 more
core   +2 more sources

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

open access: yesAdvanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding   +5 more
wiley   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Interdisciplinary mapping of body of knowledge-based agencies; A step towards understanding entrepreneurial agency [PDF]

open access: yesInterdisciplinary Studies in the Humanities
Entrepreneurial agency, defined as people's ability to discover and exploit business opportunities and create new value, is a complicated notion that necessitates an interdisciplinary approach and the integration of various views.
Z. Behrouzazar   +4 more
doaj   +1 more source

Dual-system theory and the role of consciousness in intentional action [PDF]

open access: yes, 2019
According to the standard view in philosophy, intentionality is the mark of genuine action. In psychology, human cognition and agency are now widely explained in terms of the workings of two distinct systems (or types of processes), and intentionality is
Schlosser, Markus E.
core  

Ubiquitous Place Names Standardization and Study in Indonesia [PDF]

open access: yes, 2015
Place names play a vital role in human society. Names exist in all languages and place names are an indispensible part of International communication. This has been acknowledged by the establishment of the United Nations Group of Experts on Geographical ...
Lauder, A. F. (Allan)   +1 more
core   +2 more sources

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